Intraneural edema following exposure to vibration

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift


Peripheral neuropathy represents a well-known complication from long-term exposure to vibration. In the present study an experimental model is presented with the purpose of analyzing the formation of intraneural edema following vibration exposure. Vibration (82 Hz, peak-to-peak amplitude 0.21 mm) was induced in the hind limb of rats by the use of vibrating electric motors during 4 h/d for 5 d. Tracer techniques (with albumin Evans blue and horseradish peroxidase) were used to study the permeability of intraneural microvessels after the vibration exposure on day 5. It was found that the vibration trauma in this model induced epineurial edema in the sciatic nerve. It is hypothesized that the formation of intraneural edema may be an important pathophysiological factor in the occurrence of vibration-induced neuropathy.


Enheter & grupper
Externa organisationer
  • Finnish Institute of Occupational Health
  • Göteborgs universitet

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Neurovetenskaper
  • Dermatologi och venereologi


Sidor (från-till)326-9
Antal sidor4
TidskriftScandinavian Journal of Work, Environment and Health
Utgåva nummer4
StatusPublished - 1987 aug
Peer review utfördJa