Investigation of the fetal heart circulation in an animal model using contrast enhanced ultrasound

Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKonferenspaper i proceeding

Abstract

To assess the distribution of blood from the umbilical vein (UMV), inferior vena cava (IVC) and superior vena cava (SVC) to either side of the fetal lamb heart by using ultrasound enhanced contrast agent imaging. By injection of ultrasound contrast agents (UCA) in UMV, IVC or SVC, the blood from these vessels was tracked, as it then was highly echogenic. By evaluating the image intensity within the heart ventricles, the relative concentrations of blood could be determined. The study was performed in 19 near term fetal lambs of mixed breed, with a mean gestational age of 136 days (range 134-136). Ultrasound contrast agent was injected at a constant rate of 1 ml/min, to ensure that a constant level of contrast agent would be obtained in both sides of the heart. Results: the median percentages of blood distributed to the left ventricle when injecting contrast in UMV, IVC, and SVC, was 68%, 67%, and 21% respectively. These numbers compare well with previously published data, except the recorded percentage distributed from the IVC. This could be a methodological error as well as a result of the mild hypoxia, or an actual increased capacity of the left ventricle at this gestational age

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Reproduktionsmedicin och gynekologi

Nyckelord

Originalspråkengelska
Titel på värdpublikationProceedings of the International Federation for Medical & Biomedical Engineering. 13th Nordic Baltic Conference on Biomedical Engineering and Medical Physics
FörlagInt. Federation for Medical and Biological Eng
Sidor125-126
ISBN (tryckt)91-7305-910-2
StatusPublished - 2005
PublikationskategoriForskning
Peer review utfördJa
EvenemangProceedings of the International Federation for Medical & Biomedical Engineering. 13th Nordic Baltic Conference on Biomedical Engineering and Medical Physics - Umea, Sverige
Varaktighet: 2005 jun 132005 jun 17

Konferens

KonferensProceedings of the International Federation for Medical & Biomedical Engineering. 13th Nordic Baltic Conference on Biomedical Engineering and Medical Physics
LandSverige
OrtUmea
Period2005/06/132005/06/17