Isolation of rat major histocompatibility genes expressed in pancreatic β-cells

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The probable role of cell surface antigens in the development of juvenile diabetes necessitates a detailed study of the proteins expressed on the surface of pancreatic β-cells. A gene library composed of genes expressed in β-cells was constructed to provide a source of low abundance genes from those cells. Initial studies with this library have led to the isolation of three genes which share nucleotide and amino acid sequence homology with mouse and human class I major histocompatibility antigens.


Externa organisationer
  • Hagedorn Research Institute
Sidor (från-till)1135-1138
Antal sidor4
TidskriftActa Biologica et Medica Germanica
Utgåva nummer12
StatusPublished - 1983 jan 1
Peer review utfördJa
Externt publiceradJa