Kernel-based Estimate of the Insulin Action of Rapid-Acting Insulin in Home-Monitored Data

Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKonferenspaper i proceeding

Abstract

To improve glycemic control in insulin-dependent diabetes, estimates of the glucose- lowering effect of insulin-the insulin action (IA)-and the dynamics thereof are essential. The current practice relies on generic estimates of the dynamic shape of the IA and rules-of-thumb to assess the total glucose-lowering effect. In this paper we present individualized estimates based on home-monitored data, incorporating a kernel-based estimate that also accounts for the nonlinear behavior of the IA across the glucose range. The method is successfully validated on 29 patients on continuous insulin pump therapy.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Medicinsk bioteknik
Originalspråkengelska
Titel på värdpublikationIFAC-PapersOnLine
FörlagIFAC
Sidor715-720
Antal sidor5
Volym48
Utgåva28
StatusPublished - 2015
PublikationskategoriForskning
Peer review utfördJa

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