Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia: Results from the Betula Cohort in Northern Sweden

Forskningsoutput: TidskriftsbidragÖversiktsartikel

Abstract

Exposure to fine particulate air pollution (PM2.5) is emerging as a risk factor for Alzheimer's disease (AD), but existing studies are still limited and heterogeneous. We have previously studied the association between dementia (AD and vascular dementia) and PM2.5 stemming from vehicle exhaust and wood-smoke in the Betula cohort in Northern Sweden. The aim of this commentary is to estimate the association between total PM2.5 and dementia in the Betula cohort, which is more relevant to include in future meta-estimates than the source-specific estimates. The hazard ratio for incident dementia associated with a 1µg/m3 increase in local PM2.5 was 1.38 (95% confidence interval: 0.99 -1.92). The interpretation of our results is that they indicate an association between local contrasts in concentration of PM2.5 at the residential address and incidence of dementia in a low-level setting.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Umeå University
  • Swedish Meteorological and Hydrological Institute
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Miljömedicin och yrkesmedicin

Nyckelord

Originalspråkengelska
Sidor (från-till)83-85
Antal sidor3
TidskriftJournal of Alzheimer's Disease
Volym81
Utgåva nummer1
StatusPublished - 2021
PublikationskategoriForskning
Peer review utfördJa