Mapping of QTL for Body Conformation and Behavior in Cattle

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift


Genome scans for quantitative trait loci (QTL) in farm animals have concentrated on primary production and health traits, and information on QTL for other important traits is rare. We performed a whole genome scan in a granddaughter design to detect QTL affecting body conformation and behavior in dairy cattle. The analysis included 16 paternal half-sib families of the Holstein breed with 872 sons and 264 genetic markers. The markers were distributed across all 29 autosomes and the pseudoautosomal region of the sex chromosomes with average intervals of 13.9 cM and covering an estimated 3155.5 cM. All families were analyzed jointly for 22 traits using multimarker regression and significance thresholds determined empirically by permutation. QTL that exceeded the experiment-wise significance threshold (5% level) were detected on chromosome 6 for foot angle, teat placement, and under depth, and on chromosome 29 for temperament. QTL approaching experiment-wise significance (10% level) were located on chromosome 6 for general of feet and legs and general quality of under, on chromosome 13 for teat length, on chromosome 23 for general quality of feet and legs, and on chromosome 29 for milking speed. An additional 51 QTL significant at the 5% chromosome-wise level were distributed over 21 chromosomes. This study provides the first evidence for QTL involved in behavior of dairy cattle and identifies QTL for udder conformation on chromosome 6 that could form the basis of recently reported QTL for clinical mastitis.


  • Stefan Hiendleder
  • H. Thomsen
  • N. Reinsch
  • J. Bennewitz
  • B. Leyhe-Horn
  • C. Looft
  • N. Xu
  • I. Medjugorac
  • I. Russ
  • C. Kühn
  • G. A. Brockmann
  • J. Blümel
  • B. Brenig
  • F. Reinhardt
  • R. Reents
  • G. Averdunk
  • M. Schwerin
  • M. Förster
  • E. Kalm
  • G. Erhardt
Externa organisationer
  • University of Kiel
Sidor (från-till)496-506
Antal sidor11
TidskriftJournal of Heredity
StatusPublished - 2003 nov 1
Peer review utfördJa
Externt publiceradJa