Mechanism of metabolite transfer in coupled two-enzyme reactions involving aldolase

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Transient-state kinetic experiments and analyses have been performed to examine the validity of hitherto unchallenged evidence proposed to be indicative of a channelled transfer of triose phosphates from aldolase to glyceraldehyde-3-phosphate dehydrogenase and glycerol-3-phosphate dehydrogenase. The results lend no support to such proposals, but show that the kinetic behaviour of the examined aldolase-dehydrogenase reactions is fully consistent with a free-diffusion mechanism of metabolite transfer.

Detaljer

Författare
  • Henrik Pettersson
  • Gösta Pettersson
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Biologiska vetenskaper

Nyckelord

Originalspråkengelska
Sidor (från-till)371-376
TidskriftEuropean Journal of Biochemistry
Volym262
Utgåva nummer2
StatusPublished - 1999
PublikationskategoriForskning
Peer review utfördJa