Mechanism of NADH transfer among dehydrogenases

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Steady-state and transient-state kinetic experiments have been performed to test the proposal that there is a direct (channelled) transfer of NADH from one dehydrogenase to another if the two enzymes exhibit distinct chiral coenzyme specificity (A-side vs. B-side). The results lend no support to this proposal, but are fully consistent with a free-diffusion mechanism of NADH transfer irrespective of the chiral specificity of the enzymes.

Detaljer

Författare
  • Wilma Martinez Arias
  • Henrik Pettersson
  • Gösta Pettersson
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Medicinska grundvetenskaper

Nyckelord

Originalspråkengelska
Sidor (från-till)149-156
TidskriftBBA - Protein Structure and Molecular Enzymology
Volym1385
Utgivningsnummer1
StatusPublished - 1998
PublikationskategoriForskning
Peer review utfördJa