Metabolic Syndrome and Endometrial Carcinoma

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Metabolic Syndrome and Endometrial Carcinoma. / Bjorge, Tone; Stocks, Tanja; Lukanova, Annekatrin; Tretli, Steinar; Selmer, Randi; Manjer, Jonas; Rapp, Kilian; Ulmer, Hanno; Almquist, Martin; Concin, Hans; Hallmans, Goran; Jonsson, Hakan; Stattin, Par; Engeland, Anders.

I: American Journal of Epidemiology, Vol. 171, Nr. 8, 2010, s. 892-902.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Harvard

Bjorge, T, Stocks, T, Lukanova, A, Tretli, S, Selmer, R, Manjer, J, Rapp, K, Ulmer, H, Almquist, M, Concin, H, Hallmans, G, Jonsson, H, Stattin, P & Engeland, A 2010, 'Metabolic Syndrome and Endometrial Carcinoma', American Journal of Epidemiology, vol. 171, nr. 8, s. 892-902. https://doi.org/10.1093/aje/kwq006

APA

Bjorge, T., Stocks, T., Lukanova, A., Tretli, S., Selmer, R., Manjer, J., ... Engeland, A. (2010). Metabolic Syndrome and Endometrial Carcinoma. American Journal of Epidemiology, 171(8), 892-902. https://doi.org/10.1093/aje/kwq006

CBE

Bjorge T, Stocks T, Lukanova A, Tretli S, Selmer R, Manjer J, Rapp K, Ulmer H, Almquist M, Concin H, Hallmans G, Jonsson H, Stattin P, Engeland A. 2010. Metabolic Syndrome and Endometrial Carcinoma. American Journal of Epidemiology. 171(8):892-902. https://doi.org/10.1093/aje/kwq006

MLA

Vancouver

Author

Bjorge, Tone ; Stocks, Tanja ; Lukanova, Annekatrin ; Tretli, Steinar ; Selmer, Randi ; Manjer, Jonas ; Rapp, Kilian ; Ulmer, Hanno ; Almquist, Martin ; Concin, Hans ; Hallmans, Goran ; Jonsson, Hakan ; Stattin, Par ; Engeland, Anders. / Metabolic Syndrome and Endometrial Carcinoma. I: American Journal of Epidemiology. 2010 ; Vol. 171, Nr. 8. s. 892-902.

RIS

TY - JOUR

T1 - Metabolic Syndrome and Endometrial Carcinoma

AU - Bjorge, Tone

AU - Stocks, Tanja

AU - Lukanova, Annekatrin

AU - Tretli, Steinar

AU - Selmer, Randi

AU - Manjer, Jonas

AU - Rapp, Kilian

AU - Ulmer, Hanno

AU - Almquist, Martin

AU - Concin, Hans

AU - Hallmans, Goran

AU - Jonsson, Hakan

AU - Stattin, Par

AU - Engeland, Anders

PY - 2010

Y1 - 2010

N2 - The authors examined the association between the metabolic syndrome and risk of incident endometnal and fatal uterine corpus cancer within a large prospective cohort study Approximately 290,000 women from Austria, Norway, and Sweden were enrolled during 1974-2005, with measurements of height, weight, systolic and diastolic blood pressure, and circulating levels of glucose, total cholesterol, and tnglycendes Relative risks were estimated using Cox proportional hazards regression. The metabolic syndrome was assessed as a composite z score, as the standardized sum of z scores for body mass index, blood pressure, glucose, cholesterol, and tnglycendes. A total of 917 endonnetnal carcinomas and 129 fatal cancers were identified Increased risks of incident endometnal carcinoma and fatal uterine corpus cancer were seen for the metabolic syndrome factors combined, as well as for individual factors (except for cholesterol) The relative risk of endometnal carcinoma for the metabolic syndrome was 1.37 (95% confidence interval 1 28, 1 46) per 1-unit increment of z score The positive associations between metabolic syndrome factors (both individually and combined) and endometrial carcinoma were confined to the heaviest women. The association between the metabolic syndrome and endometnal carcinoma risk seems to go beyond the risk conferred by obesity alone, particularly in women with a high body mass index

AB - The authors examined the association between the metabolic syndrome and risk of incident endometnal and fatal uterine corpus cancer within a large prospective cohort study Approximately 290,000 women from Austria, Norway, and Sweden were enrolled during 1974-2005, with measurements of height, weight, systolic and diastolic blood pressure, and circulating levels of glucose, total cholesterol, and tnglycendes Relative risks were estimated using Cox proportional hazards regression. The metabolic syndrome was assessed as a composite z score, as the standardized sum of z scores for body mass index, blood pressure, glucose, cholesterol, and tnglycendes. A total of 917 endonnetnal carcinomas and 129 fatal cancers were identified Increased risks of incident endometnal carcinoma and fatal uterine corpus cancer were seen for the metabolic syndrome factors combined, as well as for individual factors (except for cholesterol) The relative risk of endometnal carcinoma for the metabolic syndrome was 1.37 (95% confidence interval 1 28, 1 46) per 1-unit increment of z score The positive associations between metabolic syndrome factors (both individually and combined) and endometrial carcinoma were confined to the heaviest women. The association between the metabolic syndrome and endometnal carcinoma risk seems to go beyond the risk conferred by obesity alone, particularly in women with a high body mass index

KW - cohort studies

KW - endometrial neoplasms

KW - metabolic syndrome X

U2 - 10.1093/aje/kwq006

DO - 10.1093/aje/kwq006

M3 - Article

VL - 171

SP - 892

EP - 902

JO - American journal of hygiene

T2 - American journal of hygiene

JF - American journal of hygiene

SN - 0002-9262

IS - 8

ER -