Microbeam radiation therapy - Grid therapy and beyond: A clinical perspective

Forskningsoutput: TidskriftsbidragÖversiktsartikel

Abstract

Microbeam irradiation is spatially fractionated radiation on a micrometer scale. Microbeam irradiation with therapeutic intent has become known as microbeam radiation therapy (MRT). The basic concept of MRT was developed in the 1980s, but it has not yet been tested in any human clinical trial, even though there is now a large number of animal studies demonstrating its marked therapeutic potential with an exceptional normal tissue sparing effect. Furthermore, MRT is conceptually similar to macroscopic grid based radiation therapy which has been used in clinical practice for decades. In this review, the potential clinical applications of MRT are analysed for both malignant and non-malignant diseases.

Detaljer

Författare
  • Elisabeth Schültke
  • Jacques Balosso
  • Thomas Breslin
  • Guido Cavaletti
  • Valentin Djonov
  • Francois Esteve
  • Michael Grotzer
  • Guido Hildebrandt
  • Alexander Valdman
  • Jean Laissue
Enheter & grupper
Externa organisationer
  • Universitätsmedizin Rostock
  • Grenoble University Hospital
  • Skåne University Hospital
  • European Institute of Oncology
  • University of Bern
  • Kinderspital Zurich
  • Karolinska University Hospital
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Radiologi och bildbehandling
  • Cancer och onkologi
Originalspråkengelska
Artikelnummer20170073
TidskriftBritish Journal of Radiology
Volym90
Utgåva nummer1078
StatusPublished - 2017
PublikationskategoriForskning
Peer review utfördJa