Microwave-induced hyperthermia and ionizing radiation. Preliminary clinical results

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

The combination of microwave-induced (2450 MHz) hyperthermia and ionizing radiation was used in 7 patients with superficial malignant tumours, which were considered refractory to other therapy. A newly developed heating system was used, allowing for a maintained temperature at the master probe of 42.5 degrees C +/- 0.5 degrees C during 45 min, but temperature measurements at multiple sites showed a marked variation. This preliminary series indicates that the combination of hyperthermia and ionizing radiation may be useful, the response rate (complete or partial) being 8 of 8 evaluable lesions. Even previously heavily irradiated sites responded. Technical improvements are highly needed to allow for controlled heating of any tissue volume.

Detaljer

Författare
  • C-E Lindholm
  • Elisabeth Kjellén
  • Torsten Landberg
  • Per Nilsson
  • B Persson
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Cancer och onkologi
  • Klinisk medicin
  • Radiologi och bildbehandling
Originalspråkengelska
Sidor (från-till)241-254
TidskriftActa radiologica. Oncology
Volym21
Utgivningsnummer4
StatusPublished - 1982
PublikationskategoriForskning
Peer review utfördJa