Mortality and cancer morbidity among cement workers

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

OBJECTIVE:
To explore associations between exposure to cement dust and cause specific mortality and tumour morbidity, especially gastrointestinal tumours.

DESIGN:
A retrospective cohort study.

SUBJECTS AND SETTING:
2400 men, employed for at least 12 months in two Swedish cement factories.

MAIN OUTCOME MEASURES:
Cause specific morality from death certificates (1952-86). Cancer morbidity from tumour registry information (1958-86). Standardised mortality rates (SMRs; national reference rates) and standardised morbidity incidence rates (SIRs; regional reference rates) were calculated.

RESULTS:
An increased risk of colorectal cancer was found > or = 15 years since the start of employment (SIR 1.6, 95% confidence interval (95% CI) 1.1-2.3), mainly due to an increased risk for tumours in the right part of the colon (SIR 2.7, 95% CI 1.4-4.8), but not in the left part (SIR 1.0, 95% CI 0.3-2.5). There was a numerical increase of rectal cancer (SIR 1.5, 95% CI 0.8-2.5). Exposure (duration of blue collar employment)-response relations were found for right sided colon cancer. After > or = 25 years of cement work, the risk was fourfold (SIR 4.3, 95% CI 1.7-8.9). There was no excess of stomach cancer or respiratory cancer. Neither total mortality nor cause specific mortality were significantly increased.

CONCLUSIONS:
Diverging risk patterns for tumours with different localisations within the large bowel were found in the morbidity study. Long term exposure to cement dust was a risk factor for right sided colon cancer. The mortality study did not show this risk.

Detaljer

Författare
  • Kristina Jakobsson
  • Vibeke Horstmann
  • Hans Welinder
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Miljömedicin och yrkesmedicin

Nyckelord

Originalspråkengelska
Sidor (från-till)264-72
TidskriftBritish Journal of Industrial Medicine
Volym50
Utgåva nummer3
StatusPublished - 1993
PublikationskategoriForskning
Peer review utfördJa