New directions of miniaturization within the proteomics research area

Forskningsoutput: TidskriftsbidragÖversiktsartikel

Abstract

An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel- and liquid-phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing plays a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Medicinteknik
  • Analytisk kemi

Nyckelord

Originalspråkengelska
Sidor (från-till)3521-3532
TidskriftElectrophoresis
Volym24
Utgivningsnummer21
StatusPublished - 2003
PublikationskategoriForskning
Peer review utfördJa