NG2 cells, a new trail for Alzheimer's disease mechanisms?

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Neuron Glial 2 (NG2) cells are glial cells known to serve as oligodendrocyte progenitors as well as modulators of the neuronal network. Altered NG2 cell morphology and up-regulation as well as increased shedding of the proteoglycan NG2 expressed on the cell surface have been described in rodent models of brain injury. Here we describe alterations in the human NG2 cell population in response to pathological changes characteristic of Alzheimer's disease (AD).

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Neurovetenskaper
Originalspråkengelska
Artikelnummer7
TidskriftActa neuropathologica communications
Volym1
Utgivningsnummer1
StatusPublished - 2013
PublikationskategoriForskning
Peer review utfördJa

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