NG2 cells, a new trail for Alzheimer's disease mechanisms?

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NG2 cells, a new trail for Alzheimer's disease mechanisms? / Nielsen, Henrietta; Ek, Danyal; Avdic, Una; Orbjörn, Camilla; Hansson, Oskar; Veerhuis, Robert; Rozemuller, Annemieke Jm; Brun, Arne; Minthon, Lennart; Wennström, Malin.

I: Acta neuropathologica communications, Vol. 1, Nr. 1, 7, 2013.

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Nielsen, Henrietta ; Ek, Danyal ; Avdic, Una ; Orbjörn, Camilla ; Hansson, Oskar ; Veerhuis, Robert ; Rozemuller, Annemieke Jm ; Brun, Arne ; Minthon, Lennart ; Wennström, Malin. / NG2 cells, a new trail for Alzheimer's disease mechanisms?. I: Acta neuropathologica communications. 2013 ; Vol. 1, Nr. 1.

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TY - JOUR

T1 - NG2 cells, a new trail for Alzheimer's disease mechanisms?

AU - Nielsen, Henrietta

AU - Ek, Danyal

AU - Avdic, Una

AU - Orbjörn, Camilla

AU - Hansson, Oskar

AU - Veerhuis, Robert

AU - Rozemuller, Annemieke Jm

AU - Brun, Arne

AU - Minthon, Lennart

AU - Wennström, Malin

PY - 2013

Y1 - 2013

N2 - Neuron Glial 2 (NG2) cells are glial cells known to serve as oligodendrocyte progenitors as well as modulators of the neuronal network. Altered NG2 cell morphology and up-regulation as well as increased shedding of the proteoglycan NG2 expressed on the cell surface have been described in rodent models of brain injury. Here we describe alterations in the human NG2 cell population in response to pathological changes characteristic of Alzheimer's disease (AD).

AB - Neuron Glial 2 (NG2) cells are glial cells known to serve as oligodendrocyte progenitors as well as modulators of the neuronal network. Altered NG2 cell morphology and up-regulation as well as increased shedding of the proteoglycan NG2 expressed on the cell surface have been described in rodent models of brain injury. Here we describe alterations in the human NG2 cell population in response to pathological changes characteristic of Alzheimer's disease (AD).

U2 - 10.1186/2051-5960-1-7

DO - 10.1186/2051-5960-1-7

M3 - Article

VL - 1

JO - Acta neuropathologica communications

T2 - Acta neuropathologica communications

JF - Acta neuropathologica communications

SN - 2051-5960

IS - 1

M1 - 7

ER -