On-line coupling of microdialysis sampling with liquid chromatography for the determination of peptide and non-peptide leukotrienes

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

An automated on-line sampling method was developed using microdialysis as the simultaneous sampling and sample pre-treatment technique. The extraction fraction values of microdialysis probes sampling different eicosanoids were investigated. The impact of cyclodextrins in the perfusion liquid used for sampling hydrophobic eicosanoids in biological systems was also studied. The total time for one analysis was 7.6 min allowing seven measurements per hour for monitoring kinetic changes in biological systems.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Astra Draco AB
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Analytisk kemi

Nyckelord

Originalspråkengelska
Sidor (från-till)489-496
Antal sidor8
TidskriftJournal of chromatography. A
Volym823
Utgivningsnummer1-2
StatusPublished - 1998 okt 9
PublikationskategoriForskning
Peer review utfördJa