Optimizing nanovial outlet designs for improved solid-phase extraction in the integrated selective enrichment target-ISET.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

The integrated selective enrichment target is a microfluidic platform for SPE sample preparation with integrated nanocolumns, which simultaneously offers direct MALDI MS read-out. Here, we present a study on the importance of different nanocolumn outlet hole geometries and hole areas in relation to MS signal intensity and reproducibility. A design solution that provides the flow characteristics required for robust sample preparation using automated liquid handling is reported.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Medicinteknik
Originalspråkengelska
Sidor (från-till)3143-3150
TidskriftElectrophoresis
Volym33
Utgåva nummer21
StatusPublished - 2012
PublikationskategoriForskning
Peer review utfördJa