Pallidal and thalamic neurostimulation in severe tardive dystonia

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

A 70 year old woman presented with a 6 year history of medically refractory severe tardive dystonia. After informed consent, a bilateral stereotactic electrode placement targeting the ventral intermediate thalamic nucleus (VIM) and the globus pallidus internus (GPi) was performed. After bilateral stimulation of the GPi, the patient showed a clear and stable improvement of the painful dystonic syndrome within hours. Stimulation of the VIM did not improve the hyperkinetic movements and simultaneous stimulation of both the GPi and the VIM did not result in any additional benefit. The possible pathophysiological mechanisms are discussed.

Detaljer

Författare
  • T Trottenberg
  • G Paul
  • Wlodzimierz Meissner
  • K Maier-Hauff
  • C Taschner
  • A Kupsch
Externa organisationer
  • Humboldt University of Berlin
Forskningsområden

Nyckelord

Originalspråkengelska
Sidor (från-till)557-9
Antal sidor3
TidskriftJournal of Neurology, Neurosurgery and Psychiatry
Volym70
Utgivningsnummer4
StatusPublished - 2001 apr
PublikationskategoriForskning
Peer review utfördJa
Externt publiceradJa