Platelet-derived S100A8/A9 and cardiovascular disease in systemic lupus erythematosus.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

S100A8/A9, a pro-inflammatory and pro-thrombotic protein complex, is increased in several diseases and high levels predispose to cardiovascular disease (CVD). Recently, platelet S100A8/A9 synthesis was described in mouse and humans in relation to CVD. However, the role of platelet S100A8/A9 in systemic lupus erythematosus (SLE), a disease with markedly increased cardiovascular morbidity, as well as the exact platelet distribution of the S100A8/A9 proteins has not been investigated.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Cell- och molekylärbiologi
Originalspråkengelska
TidskriftArthritis & Rheumatology
Tidigt onlinedatum2016 mar 4
StatusPublished - 2016
PublikationskategoriForskning
Peer review utfördJa