Practices of Pediatric Oncology and Hematology Providers Regarding Fertility Issues: A European Survey

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BackgroundFertility is impaired in many survivors of childhood cancer following treatment. Preservation of fertility after cancer has become a central survivorship concern. Nevertheless, several doctors, patients, and families do not discuss fertility and recommendations for fertility preservation in pediatrics are still lacking. Recommendations based on scientific evidence are needed and before their development we wanted to assess the practice patterns of fertility preservation in Europe. ProceduresOn behalf of the PanCare network, we sent a questionnaire to pediatric onco-hematology institutions across Europe. The survey consisted of 21 questions assessing their usual practices around fertility preservation. ResultsOne hundred ninety-eight institutional representatives across Europe received the survey and 68 (response rate 34.3%) responded. Pre-treatment fertility counseling was offered by 64 institutions. Counseling was done by a pediatric onco-hematologist in 52% (33/64) and in 32% (20/64) by a team. The majority of institutions (53%) lacked recommendations for fertility preservation. All 64 centers offered sperm banking; eight offered testicular tissue cryopreservation for pre-pubertal males. For females, the possibility of preserving ovarian tissue was offered by 40 institutions. ConclusionsThere is a high level of interest in fertility preservation among European centers responding to our survey. However, while most recommended sperm cryopreservation, many also recommended technologies whose efficacy has not been shown. There is an urgent need for evidence-based European recommendations for fertility preservation to help survivors deal with the stressful topic of fertility. Pediatr Blood Cancer 2014;61:2054-2058. (c) 2014 Wiley Periodicals, Inc.


  • Monica Terenziani
  • Marco Spinelli
  • Momcilo Jankovic
  • Edit Bardi
  • Lars Hjorth
  • Riccardo Haupt
  • Gisela Michel
  • Julianne Byrne
Enheter & grupper

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Pediatrik


Sidor (från-till)2054-2058
TidskriftPediatric Blood & Cancer
Utgåva nummer11
StatusPublished - 2014
Peer review utfördJa