Pre-diagnostic polyphenol intake and breast cancer survival: the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.

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Pre-diagnostic polyphenol intake and breast cancer survival: the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. / Kyrø, Cecilie; Zamora-Ros, Raul; Scalbert, Augustin; Tjønneland, Anne; Dossus, Laure; Johansen, Christoffer; Bidstrup, Pernille Envold; Weiderpass, Elisabete; Christensen, Jane; Ward, Heather; Aune, Dagfinn; Riboli, Elio; His, Mathilde; Clavel-Chapelon, Françoise; Baglietto, Laura; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Floegel, Anna; Overvad, Kim; Lasheras, Cristina; Travier, Noémie; Sánchez, Maria-José; Amiano, Pilar; Chirlaque, Maria-Dolores; Ardanaz, Eva; Khaw, Kay-Tee; Wareham, Nick; Perez-Cornago, Aurora; Trichopoulou, Antonia; Lagiou, Pagona; Vasilopoulou, Effie; Masala, Giovanna; Grioni, Sara; Berrino, Franco; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Bueno-de-Mesquita, H B As; Peeters, Petra H; van Gils, Carla; Borgquist, Signe; Butt, Salma; Zeleniuch-Jacquotte, Anne; Sund, Malin; Hjartåker, Anette; Skeie, Guri; Olsen, Anja; Romieu, Isabelle.

I: Breast Cancer Research and Treatment, Vol. 154, Nr. 2, 2015, s. 389-401.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Harvard

Kyrø, C, Zamora-Ros, R, Scalbert, A, Tjønneland, A, Dossus, L, Johansen, C, Bidstrup, PE, Weiderpass, E, Christensen, J, Ward, H, Aune, D, Riboli, E, His, M, Clavel-Chapelon, F, Baglietto, L, Katzke, V, Kühn, T, Boeing, H, Floegel, A, Overvad, K, Lasheras, C, Travier, N, Sánchez, M-J, Amiano, P, Chirlaque, M-D, Ardanaz, E, Khaw, K-T, Wareham, N, Perez-Cornago, A, Trichopoulou, A, Lagiou, P, Vasilopoulou, E, Masala, G, Grioni, S, Berrino, F, Tumino, R, Sacerdote, C, Mattiello, A, Bueno-de-Mesquita, HBA, Peeters, PH, van Gils, C, Borgquist, S, Butt, S, Zeleniuch-Jacquotte, A, Sund, M, Hjartåker, A, Skeie, G, Olsen, A & Romieu, I 2015, 'Pre-diagnostic polyphenol intake and breast cancer survival: the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.', Breast Cancer Research and Treatment, vol. 154, nr. 2, s. 389-401. https://doi.org/10.1007/s10549-015-3595-9

APA

Kyrø, C., Zamora-Ros, R., Scalbert, A., Tjønneland, A., Dossus, L., Johansen, C., Bidstrup, P. E., Weiderpass, E., Christensen, J., Ward, H., Aune, D., Riboli, E., His, M., Clavel-Chapelon, F., Baglietto, L., Katzke, V., Kühn, T., Boeing, H., Floegel, A., ... Romieu, I. (2015). Pre-diagnostic polyphenol intake and breast cancer survival: the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Breast Cancer Research and Treatment, 154(2), 389-401. https://doi.org/10.1007/s10549-015-3595-9

CBE

Kyrø C, Zamora-Ros R, Scalbert A, Tjønneland A, Dossus L, Johansen C, Bidstrup PE, Weiderpass E, Christensen J, Ward H, Aune D, Riboli E, His M, Clavel-Chapelon F, Baglietto L, Katzke V, Kühn T, Boeing H, Floegel A, Overvad K, Lasheras C, Travier N, Sánchez M-J, Amiano P, Chirlaque M-D, Ardanaz E, Khaw K-T, Wareham N, Perez-Cornago A, Trichopoulou A, Lagiou P, Vasilopoulou E, Masala G, Grioni S, Berrino F, Tumino R, Sacerdote C, Mattiello A, Bueno-de-Mesquita HBA, Peeters PH, van Gils C, Borgquist S, Butt S, Zeleniuch-Jacquotte A, Sund M, Hjartåker A, Skeie G, Olsen A, Romieu I. 2015. Pre-diagnostic polyphenol intake and breast cancer survival: the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Breast Cancer Research and Treatment. 154(2):389-401. https://doi.org/10.1007/s10549-015-3595-9

MLA

Vancouver

Author

Kyrø, Cecilie ; Zamora-Ros, Raul ; Scalbert, Augustin ; Tjønneland, Anne ; Dossus, Laure ; Johansen, Christoffer ; Bidstrup, Pernille Envold ; Weiderpass, Elisabete ; Christensen, Jane ; Ward, Heather ; Aune, Dagfinn ; Riboli, Elio ; His, Mathilde ; Clavel-Chapelon, Françoise ; Baglietto, Laura ; Katzke, Verena ; Kühn, Tilman ; Boeing, Heiner ; Floegel, Anna ; Overvad, Kim ; Lasheras, Cristina ; Travier, Noémie ; Sánchez, Maria-José ; Amiano, Pilar ; Chirlaque, Maria-Dolores ; Ardanaz, Eva ; Khaw, Kay-Tee ; Wareham, Nick ; Perez-Cornago, Aurora ; Trichopoulou, Antonia ; Lagiou, Pagona ; Vasilopoulou, Effie ; Masala, Giovanna ; Grioni, Sara ; Berrino, Franco ; Tumino, Rosario ; Sacerdote, Carlotta ; Mattiello, Amalia ; Bueno-de-Mesquita, H B As ; Peeters, Petra H ; van Gils, Carla ; Borgquist, Signe ; Butt, Salma ; Zeleniuch-Jacquotte, Anne ; Sund, Malin ; Hjartåker, Anette ; Skeie, Guri ; Olsen, Anja ; Romieu, Isabelle. / Pre-diagnostic polyphenol intake and breast cancer survival: the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. I: Breast Cancer Research and Treatment. 2015 ; Vol. 154, Nr. 2. s. 389-401.

RIS

TY - JOUR

T1 - Pre-diagnostic polyphenol intake and breast cancer survival: the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.

AU - Kyrø, Cecilie

AU - Zamora-Ros, Raul

AU - Scalbert, Augustin

AU - Tjønneland, Anne

AU - Dossus, Laure

AU - Johansen, Christoffer

AU - Bidstrup, Pernille Envold

AU - Weiderpass, Elisabete

AU - Christensen, Jane

AU - Ward, Heather

AU - Aune, Dagfinn

AU - Riboli, Elio

AU - His, Mathilde

AU - Clavel-Chapelon, Françoise

AU - Baglietto, Laura

AU - Katzke, Verena

AU - Kühn, Tilman

AU - Boeing, Heiner

AU - Floegel, Anna

AU - Overvad, Kim

AU - Lasheras, Cristina

AU - Travier, Noémie

AU - Sánchez, Maria-José

AU - Amiano, Pilar

AU - Chirlaque, Maria-Dolores

AU - Ardanaz, Eva

AU - Khaw, Kay-Tee

AU - Wareham, Nick

AU - Perez-Cornago, Aurora

AU - Trichopoulou, Antonia

AU - Lagiou, Pagona

AU - Vasilopoulou, Effie

AU - Masala, Giovanna

AU - Grioni, Sara

AU - Berrino, Franco

AU - Tumino, Rosario

AU - Sacerdote, Carlotta

AU - Mattiello, Amalia

AU - Bueno-de-Mesquita, H B As

AU - Peeters, Petra H

AU - van Gils, Carla

AU - Borgquist, Signe

AU - Butt, Salma

AU - Zeleniuch-Jacquotte, Anne

AU - Sund, Malin

AU - Hjartåker, Anette

AU - Skeie, Guri

AU - Olsen, Anja

AU - Romieu, Isabelle

PY - 2015

Y1 - 2015

N2 - The aim was to investigate the association between pre-diagnostic intakes of polyphenol classes (flavonoids, lignans, phenolic acids, stilbenes, and other polyphenols) in relation to breast cancer survival (all-cause and breast cancer-specific mortality). We used data from the European Prospective Investigation into Cancer and Nutrition cohort. Pre-diagnostic usual diet was assessed using dietary questionnaires, and polyphenol intakes were estimated using the Phenol-Explorer database. We followed 11,782 breast cancer cases from time of diagnosis until death, end of follow-up or last day of contact. During a median of 6 years, 1482 women died (753 of breast cancer). We related polyphenol intake to all-cause and breast cancer-specific mortality using Cox proportional hazard models with time since diagnosis as underlying time and strata for age and country. Among postmenopausal women, an intake of lignans in the highest versus lowest quartile was related to a 28 % lower risk of dying from breast (adjusted model: HR, quartile 4 vs. quartile 1, 0.72, 95 % CI 0.53; 0.98). In contrast, in premenopausal women, a positive association between lignan intake and all-cause mortality was found (adjusted model: HR, quartile 4 vs. quartile 1, 1.63, 95 % CI 1.03; 2.57). We found no association for other polyphenol classes. Intake of lignans before breast cancer diagnosis may be related to improved survival among postmenopausal women, but may on the contrary worsen the survival for premenopausal women. This suggests that the role of phytoestrogens in breast cancer survival is complex and may be dependent of menopausal status.

AB - The aim was to investigate the association between pre-diagnostic intakes of polyphenol classes (flavonoids, lignans, phenolic acids, stilbenes, and other polyphenols) in relation to breast cancer survival (all-cause and breast cancer-specific mortality). We used data from the European Prospective Investigation into Cancer and Nutrition cohort. Pre-diagnostic usual diet was assessed using dietary questionnaires, and polyphenol intakes were estimated using the Phenol-Explorer database. We followed 11,782 breast cancer cases from time of diagnosis until death, end of follow-up or last day of contact. During a median of 6 years, 1482 women died (753 of breast cancer). We related polyphenol intake to all-cause and breast cancer-specific mortality using Cox proportional hazard models with time since diagnosis as underlying time and strata for age and country. Among postmenopausal women, an intake of lignans in the highest versus lowest quartile was related to a 28 % lower risk of dying from breast (adjusted model: HR, quartile 4 vs. quartile 1, 0.72, 95 % CI 0.53; 0.98). In contrast, in premenopausal women, a positive association between lignan intake and all-cause mortality was found (adjusted model: HR, quartile 4 vs. quartile 1, 1.63, 95 % CI 1.03; 2.57). We found no association for other polyphenol classes. Intake of lignans before breast cancer diagnosis may be related to improved survival among postmenopausal women, but may on the contrary worsen the survival for premenopausal women. This suggests that the role of phytoestrogens in breast cancer survival is complex and may be dependent of menopausal status.

U2 - 10.1007/s10549-015-3595-9

DO - 10.1007/s10549-015-3595-9

M3 - Article

C2 - 26531755

VL - 154

SP - 389

EP - 401

JO - Breast Cancer Research and Treatment

JF - Breast Cancer Research and Treatment

SN - 0167-6806

IS - 2

ER -