Prenylated isoflavanone from the roots of Erythrina sigmoidea

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Abstract

A novel prenylated isoflavanone, sigmoidin I, has been isolated from the roots of Erythrina sigmoidea, in addition to the known isoflavones, corylin and neobavaisoflavone and the known pterocarpan, phaseollidin. Its structure was established as 7,4'-dihydroxy-3'-methoxy-5'-(3-methylbut-2-enyl) isoflavanone by means of spectroscopic analyses and chemical transformations. Neobavaisoflavone displayed antifungal potency in vitro with minimum inhibitory concentrations against Aspergillus fumigatus and Cryptococcus neoformans, of 50 mg ml-1.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Dermatologi och venereologi

Nyckelord

Originalspråkengelska
Sidor (från-till)1047-1051
TidskriftPhytochemistry
Volym36
Utgåva nummer4
StatusPublished - 1994
PublikationskategoriForskning
Peer review utfördJa