Pressure distribution in mammography: compression of breasts with malignant tumor masses

Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKonferenspaper i proceeding

Abstract

The pressure distribution over a compressed breast is in general heterogeneous. In this study we investigated the pressure distribution over compressed breasts with tumor masses. Twenty-two women either recalled for work-up of findings suspicious for breast cancer in the screening program or with clinically suspected findings were included in the study. Twenty-one lesions turned out to be malignant and one benign. The distribution of compression pressure was measured using thin FSR (Force Sensing Resistor) pressure sensors attached to the compression plate. The pressure over the breast was ascertained by acquiring an x-ray image of the compressed breast with the pressure sensors present. The pressure data and the mammogram were used to create a composite image with pressure data displayed as a color overlay. The malignant tumor area generally matched an elevated pressure area and this pressure was generally higher than the pressure over surrounding parenchyma. In 11 out of 22 (50%) subjects the maximum pressure over the breast was located over the tumor. Only 4 out of 22 (18%) masses had a lower tumor mean pressure compared to the mean pressure over the breast (including one small < 10 mm tumor and one benign structure). The results suggest that tumors are stiffer, thus, absorbing more pressure compared to the surrounding parenchyma and that this property can be quantified. Refined pressure techniques could possibly be used to demonstrate the relative elasticity distribution in breast tissue, which might provide valuable differential diagnostic information.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Radiologi och bildbehandling

Nyckelord

Originalspråkengelska
Titel på värdpublikationMedical Imaging 2013: Physics of Medical Imaging
FörlagSPIE
Sidor86684E
Volym8668
StatusPublished - 2013
PublikationskategoriForskning
Peer review utfördJa
EvenemangConference on Medical Imaging - Physics of Medical Imaging, 2013 - Lake Buena Vista, FL, USA
Varaktighet: 2013 feb 112013 feb 14

Publikationsserier

Namn
Volym8668
ISSN (tryckt)0277-786X
ISSN (elektroniskt)1996-756X

Konferens

KonferensConference on Medical Imaging - Physics of Medical Imaging, 2013
LandUSA
OrtLake Buena Vista, FL
Period2013/02/112013/02/14