Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study

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Introduction: Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple different assessment protocols. A large multinational group of clinicians and researchers participated in a two-phase Vascular Impairment of Cognition Classification Consensus Study (VICCCS) to agree on principles (VICCCS-1) and protocols (VICCCS-2) for diagnosis of VCI. We present VICCCS-2. Methods: We used VICCCS-1 principles and published diagnostic guidelines as points of reference for an online Delphi survey aimed at achieving consensus on clinical diagnosis of VCI. Results: Six survey rounds comprising 65–79 participants agreed guidelines for diagnosis of VICCCS-revised mild and major forms of VCI and endorsed the National Institute of Neurological Disorders–Canadian Stroke Network neuropsychological assessment protocols and recommendations for imaging. Discussion: The VICCCS-2 suggests standardized use of the National Institute of Neurological Disorders–Canadian Stroke Network recommendations on neuropsychological and imaging assessment for diagnosis of VCI so as to promote research collaboration.


  • VICCCS group
  • Olivia A. Skrobot
  • Sandra E. Black
  • Christopher Chen
  • Charles DeCarli
  • Timo Erkinjuntti
  • Gary A. Ford
  • Rajesh N. Kalaria
  • John O'Brien
  • Leonardo Pantoni
  • Florence Pasquier
  • Gustavo C. Roman
  • Anders Wallin
  • Perminder Sachdev
  • Ingmar Skoog
  • E. Englund (Medarbetare)
Enheter & grupper
Externa organisationer
  • University of Bristol
  • University of Toronto
  • National University of Singapore
  • University of California, Davis
  • Helsinki University Central Hospital
  • University of Oxford
  • University of Newcastle upon Tyne
  • University of Cambridge
  • University of Florence
  • University of Lille
  • Sahlgrenska University Hospital
  • Prince of Wales Hospital
  • University of Helsinki
  • Houston Methodist
  • Göteborgs universitet
  • University of New South Wales

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Neurologi


Sidor (från-till)280-292
Antal sidor13
TidskriftAlzheimer's and Dementia
StatusPublished - 2018 mar 1
Peer review utfördJa