Psychosocial health and levels of employment in 851 hypopituitary Swedish patients on long-term GH therapy.

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Psychosocial health and levels of employment in 851 hypopituitary Swedish patients on long-term GH therapy. / Holmer, Helene; Svensson, Johan; Rylander, Lars; Johannsson, Gudmundur; Rosén, Thord; Bengtsson, Bengt A; Thorén, Marja; Höybye, Charlotte; Degerblad, Marie; Bramnert, Margareta; Hägg, Erik; Engström, Britt Edén; Ekman, Bertil; Erfurth, Eva Marie.

I: Psychoneuroendocrinology, Vol. 38, Nr. 6, 2013, s. 842-852.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Harvard

Holmer, H, Svensson, J, Rylander, L, Johannsson, G, Rosén, T, Bengtsson, BA, Thorén, M, Höybye, C, Degerblad, M, Bramnert, M, Hägg, E, Engström, BE, Ekman, B & Erfurth, EM 2013, 'Psychosocial health and levels of employment in 851 hypopituitary Swedish patients on long-term GH therapy.', Psychoneuroendocrinology, vol. 38, nr. 6, s. 842-852. https://doi.org/10.1016/j.psyneuen.2012.09.008

APA

CBE

Holmer H, Svensson J, Rylander L, Johannsson G, Rosén T, Bengtsson BA, Thorén M, Höybye C, Degerblad M, Bramnert M, Hägg E, Engström BE, Ekman B, Erfurth EM. 2013. Psychosocial health and levels of employment in 851 hypopituitary Swedish patients on long-term GH therapy. Psychoneuroendocrinology. 38(6):842-852. https://doi.org/10.1016/j.psyneuen.2012.09.008

MLA

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Author

Holmer, Helene ; Svensson, Johan ; Rylander, Lars ; Johannsson, Gudmundur ; Rosén, Thord ; Bengtsson, Bengt A ; Thorén, Marja ; Höybye, Charlotte ; Degerblad, Marie ; Bramnert, Margareta ; Hägg, Erik ; Engström, Britt Edén ; Ekman, Bertil ; Erfurth, Eva Marie. / Psychosocial health and levels of employment in 851 hypopituitary Swedish patients on long-term GH therapy. I: Psychoneuroendocrinology. 2013 ; Vol. 38, Nr. 6. s. 842-852.

RIS

TY - JOUR

T1 - Psychosocial health and levels of employment in 851 hypopituitary Swedish patients on long-term GH therapy.

AU - Holmer, Helene

AU - Svensson, Johan

AU - Rylander, Lars

AU - Johannsson, Gudmundur

AU - Rosén, Thord

AU - Bengtsson, Bengt A

AU - Thorén, Marja

AU - Höybye, Charlotte

AU - Degerblad, Marie

AU - Bramnert, Margareta

AU - Hägg, Erik

AU - Engström, Britt Edén

AU - Ekman, Bertil

AU - Erfurth, Eva Marie

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Pediatrics/Urology/Gynecology/Endocrinology (013240400), Department of Electroscience (011041000), Division of Occupational and Environmental Medicine (013078001), Medicine (Lund) (013230025), Paediatric Endocrinology Research Group (013243010)

PY - 2013

Y1 - 2013

N2 - CONTEXT: The psychosocial health and working capacity in hypopituitary patients receiving long-term growth hormone (GH) therapy are unknown. OBJECTIVE: Psychosocial health and levels of employment were compared between GH deficient (GHD) patients on long-term replacement and the general population. DESIGN AND PARTICIPANTS: In a Swedish nationwide study, 851 GHD patients [101 childhood onset (CO) and 750 adult onset (AO)] and 2622 population controls answered a questionnaire regarding current living, employment and educational level, alcohol consumption and smoking habits. The median time on GH therapy for both men and women with CO GHD was 9 years and for AO GHD 6 years, respectively. RESULTS: As compared to the controls, the GHD patients were less often working full time, more often on sick leave/disability pension, and to a larger extent alcohol abstainers and never smokers (all; P<0.05). Predominantly CO GHD women and men, but to some extent also AO GHD women and men, lived less frequently with a partner and more often with their parents. Particularly AO GHD craniopharyngioma women used more antidepressants, while AO GHD men with a craniopharyngioma used more analgesics. CONCLUSIONS: A working capacity to the level of the general population was not achieved among hypopituitary patients, although receiving long-term GH therapy. Patients were less likely to use alcohol and tobacco. The CO GHD population lived a less independent life.

AB - CONTEXT: The psychosocial health and working capacity in hypopituitary patients receiving long-term growth hormone (GH) therapy are unknown. OBJECTIVE: Psychosocial health and levels of employment were compared between GH deficient (GHD) patients on long-term replacement and the general population. DESIGN AND PARTICIPANTS: In a Swedish nationwide study, 851 GHD patients [101 childhood onset (CO) and 750 adult onset (AO)] and 2622 population controls answered a questionnaire regarding current living, employment and educational level, alcohol consumption and smoking habits. The median time on GH therapy for both men and women with CO GHD was 9 years and for AO GHD 6 years, respectively. RESULTS: As compared to the controls, the GHD patients were less often working full time, more often on sick leave/disability pension, and to a larger extent alcohol abstainers and never smokers (all; P<0.05). Predominantly CO GHD women and men, but to some extent also AO GHD women and men, lived less frequently with a partner and more often with their parents. Particularly AO GHD craniopharyngioma women used more antidepressants, while AO GHD men with a craniopharyngioma used more analgesics. CONCLUSIONS: A working capacity to the level of the general population was not achieved among hypopituitary patients, although receiving long-term GH therapy. Patients were less likely to use alcohol and tobacco. The CO GHD population lived a less independent life.

U2 - 10.1016/j.psyneuen.2012.09.008

DO - 10.1016/j.psyneuen.2012.09.008

M3 - Article

VL - 38

SP - 842

EP - 852

JO - Psychoneuroendocrinology

T2 - Psychoneuroendocrinology

JF - Psychoneuroendocrinology

SN - 1873-3360

IS - 6

ER -