Regional motion correction for in vivo photoacoustic imaging in humans using interleaved ultrasound images

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

In translation from preclinical to clinical studies using photoacoustic imaging, motion artifacts represent a major issue. In this study the feasibility of an in-house algorithm, referred to as intensity phase tracking (IPT), for regional motion correction of in vivo human photoacoustic (PA) images was demonstrated. The algorithm converts intensity to phase-information and performs 2D phase-tracking on interleaved ultrasound images. The radial artery in eight healthy volunteers was imaged using an ultra-high frequency photoacoustic system. PA images were motion corrected and evaluated based on PA image similarities. Both controlled measurements using a computerized stepping motor and free-hand measurements were evaluated. The results of the controlled measurements show that the tracking corresponded to 97 ± 6% of the actual movement. Overall, the mean square error between PA images decreased by 52 ± 15% and by 43 ± 19% when correcting for controlled- and free-hand induced motions, respectively. The results show that the proposed algorithm could be used for motion correction in photoacoustic imaging in humans.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Skåne University Hospital
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Radiologi och bildbehandling
  • Oftalmologi

Nyckelord

  • Image quality, In vivo imaging, Optical flow, Photoacoustic imaging, Spatial resolution, Spectral imaging
Originalspråksvenska
Sidor (från-till)3312-3322
Antal sidor11
TidskriftBiomedical Optics Express
Volym12
Utgåva nummer6
StatusPublished - 2021 maj 12
PublikationskategoriForskning
Peer review utfördJa