RIFM fragrance ingredient safety assessment, allyl phenylacetate, CAS registry number 1797-74-6.
Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift
The use of this material under current use conditions is supported by the existing information. This material was evaluated for Genotoxicity, Repeated Dose Toxicity, Developmental Toxicity, Reproductive Toxicity, Local Respiratory Toxicity, Phototoxicity, Skin Sensitization potential as well as Environmental assessment. Repeated Dose Toxicity was determined to have the most conservative systemic exposure derived NO[A]EL of 25 mg/kg/day, based on a 13-week subchronic toxicity and 103-week chronic carcinogenicity studies in rats and mice on a read across analog, that resulted in a MOE of 47170 considering 100% absorption from skin contact and inhalation. A MOE of >100 is deemed acceptable.
|Enheter & grupper|
Ämnesklassifikation (UKÄ) – OBLIGATORISK
|Tidskrift||Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association|
|Tidigt onlinedatum||2015 mar 25|
|Status||Published - 2015|
|Peer review utförd||Ja|