Risk and risk estimation of placental abruption.

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Risk and risk estimation of placental abruption. / Lindqvist, Pelle; Happach, Catharina.

I: European Journal of Obstetrics, Gynecology, and Reproductive Biology, Vol. 126, Nr. Sep 29, 2006, s. 160-164.

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Lindqvist, Pelle ; Happach, Catharina. / Risk and risk estimation of placental abruption. I: European Journal of Obstetrics, Gynecology, and Reproductive Biology. 2006 ; Vol. 126, Nr. Sep 29. s. 160-164.

RIS

TY - JOUR

T1 - Risk and risk estimation of placental abruption.

AU - Lindqvist, Pelle

AU - Happach, Catharina

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Obstetrics and Gynaecology (013242700), Pediatrics/Urology/Gynecology/Endocrinology (013240400)

PY - 2006

Y1 - 2006

N2 - Objective: Several variables related to increased risk of placental abruption are also risk factors for venous thromboembolism. Prior second trimester-, third trimester, and repeated fetal loss are reported to be associated to thrombophilias. However, it is yet not known if they are also related to placental abruption. Study design: A retrospective case-control study of 161 women with placental abruption and 2371 unselected gravidae without placental abruption. The medical files were scrutinized and the selected variables were investigated in relation to the development of placental abruption. Results: As compared to controls, previous second trimester-, third trimester-, repeated fetal loss, and prior placental abruption were related to a 3-, 13-, 3-, and a 25-fold increased risk of placental abruption, respectively. Several other factors were associated with a roughly three-fold increased risk such as: preeclampsia, IUGR, high maternal age (>35), family history of venous thromboembolism, smoking, and multiple birth. A risk score was created and as compared with those with no risk factors present, the risk of placental abruption was increasing from 2.5-fold for those with risk score = 1, to almost 100-fold for risk score 4 or above. Conclusion: Easily obtainable information might be used to classify the risk of placental abruption. (C) 2005 Elsevier Ireland Ltd. All rights reserved.

AB - Objective: Several variables related to increased risk of placental abruption are also risk factors for venous thromboembolism. Prior second trimester-, third trimester, and repeated fetal loss are reported to be associated to thrombophilias. However, it is yet not known if they are also related to placental abruption. Study design: A retrospective case-control study of 161 women with placental abruption and 2371 unselected gravidae without placental abruption. The medical files were scrutinized and the selected variables were investigated in relation to the development of placental abruption. Results: As compared to controls, previous second trimester-, third trimester-, repeated fetal loss, and prior placental abruption were related to a 3-, 13-, 3-, and a 25-fold increased risk of placental abruption, respectively. Several other factors were associated with a roughly three-fold increased risk such as: preeclampsia, IUGR, high maternal age (>35), family history of venous thromboembolism, smoking, and multiple birth. A risk score was created and as compared with those with no risk factors present, the risk of placental abruption was increasing from 2.5-fold for those with risk score = 1, to almost 100-fold for risk score 4 or above. Conclusion: Easily obtainable information might be used to classify the risk of placental abruption. (C) 2005 Elsevier Ireland Ltd. All rights reserved.

KW - placental abruption

KW - risk score

KW - fetal loss

KW - prediction

U2 - 10.1016/j.ejogrb.2005.08.003

DO - 10.1016/j.ejogrb.2005.08.003

M3 - Article

VL - 126

SP - 160

EP - 164

JO - European Journal of Obstetrics, Gynecology, and Reproductive Biology

JF - European Journal of Obstetrics, Gynecology, and Reproductive Biology

SN - 0301-2115

IS - Sep 29

ER -