Solubilisation of model adjuvants by Pluronic block copolymers.
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The effect of two model adjuvants (benzyl benzoate and benzyl alcohol) on the structure and dynamics of three Pluronic triblock copolymers (P85, P105 and F127) was studied using small-angle neutron scattering and pulsed-field gradient NMR. The two adjuvants studied have different aqueous solubilities. It was found that both adjuvants promoted the micellisation of the Pluronic block copolymers. In addition they lead to a swelling of the micelles, as shown by small-angle neutron scattering. From the pulsed-field gradient NMR results it was possible to determine the amount of adjuvant bound to the micelles.
Ämnesklassifikation (UKÄ) – OBLIGATORISK
|Tidskrift||Journal of Colloid and Interface Science|
|Tidigt onlinedatum||2010 jan 11|
|Status||Published - 2010|
|Peer review utförd||Ja|