Sorting breast cancer cells based on deformability

Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKonferenspaper i proceeding

Abstract

Due to their direct coupling to the physiology of the cells, the physical properties are especially attractive as markers for sorting and characterization of cancer cells. Where molecular surface markers are lacking, the physical properties can instead serve as inherent markers for separation. This is especially interesting for cancer cells where there are indications that soft cells are more metastatic than hard cells. Our work is expected to provide a deeper understanding of deformability based sorting based on deterministic lateral displacement (DLD). This will subsequently be used to optimize DLD devices for characterization and fractionation of cancer cells into subpopulations of different mechanical properties. Our aim is to develop a device to help oncologists gain more accurate prognoses and better monitoring of the effect of treatment.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Biomedicinsk laboratorievetenskap/teknologi
  • Cancer och onkologi

Nyckelord

Originalspråkengelska
Titel på värdpublikationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
FörlagChemical and Biological Microsystems Society
Sidor364-366
Antal sidor3
ISBN (elektroniskt)9780979806483
StatusPublished - 2015
PublikationskategoriForskning
Peer review utfördJa
Evenemang19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Sydkorea, Republiken Korea
Varaktighet: 2015 okt 252015 okt 29

Konferens

Konferens19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
LandSydkorea, Republiken Korea
OrtGyeongju
Period2015/10/252015/10/29

Relaterad forskningsoutput

Si Hoai Trung Tran, 2019 maj 20, Department of Physics, Lund University. 67 s.

Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

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