Static and dynamic cardiac modelling: Initial strides and results towards a quantitatively accurate mechanical heart model

Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKonferenspaper i proceeding

Abstract

Magnetic Resonance Imaging (MRI) has exhibited significant potential for quantifying cardiac function and dysfunction in the mouse. Recent advances in highresolution cardiac MR imaging techniques have contributed to the development of acquisition approaches that allow fast and accurate description of anatomic structures, and accurate surface and finite element (FE) mesh model constructions for study of global mechanical function in normal and transgenic mice. This study presents work in progress for construction of quantitatively accurate threedimensional (3D) and 4D dynamic surface and FE models of murine left ventricular (LV) muscle in C57BL/6J (n=10) mice. Constructed models are subsequently imported into commercial software packages for the solution of the constitutive equations that characterize mechanical function, including computation of the stress and strain fields. They are further used with solid-free form fabrication processes to construct model-based material renditions of the human and mouse hearts.

Detaljer

Författare
Externa organisationer
  • University of Cyprus
  • Duke University
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Medicinteknik

Nyckelord

Originalspråkengelska
Titel på värdpublikation2010 7th IEEE International Symposium on Biomedical Imaging
Undertitel på gästpublikationFrom Nano to Macro, ISBI 2010 - Proceedings
FörlagIEEE - Institute of Electrical and Electronics Engineers Inc.
Sidor496-499
Antal sidor4
ISBN (tryckt)9781424441266
StatusPublished - 2010 aug 9
PublikationskategoriForskning
Peer review utfördJa
Externt publiceradJa
Evenemang7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Rotterdam, Nederländerna
Varaktighet: 2010 apr 142010 apr 17

Konferens

Konferens7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010
LandNederländerna
OrtRotterdam
Period2010/04/142010/04/17