Suicidal Intent and the HPA-Axis Characteristics of Suicide Attempters with Major Depressive Disorder and Adjustment Disorders.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

The main purpose of the study was to investigate Hypothalamic-Pituitary-Adrenal (HPA) axis characteristics in relation to suicidal intent among suicide attempters with Major Depressive Disorder (MDD) and Adjustment Disorders (AD). The relationship between suicidal intent, assessed by means of the Suicidal Intent Scale (SIS), and serum cortisol after a Dexamethasone Suppression Test (DST) was investigated in 78 suicide attempters, divided into diagnostic subgroups. There was a significant negative correlation between suicidal intent and post DST cortisol in patients with MDD. Our findings may be attributed to pathophysiological processes, where a high suicidal intent is revealed during a potential chronic course of MDD, which in turnresults in a seemingly normal stress system.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Psykiatri

Nyckelord

Originalspråkengelska
Sidor (från-till)197-207
TidskriftArchives of Suicide Research
Volym12
Utgivningsnummer3
StatusPublished - 2008
PublikationskategoriForskning
Peer review utfördJa

Relaterad forskningsoutput

Vang, F., 2012, Lund University. 158 s.

Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

Daniel Lindqvist, 2010, Lund University, Faculty of Medicine. 104 s.

Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

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