Survival in amoeba-a major selection pressure on the presence of bacterial copper and zinc resistance determinants? Identification of a "copper pathogenicity island"

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Survival in amoeba-a major selection pressure on the presence of bacterial copper and zinc resistance determinants? Identification of a "copper pathogenicity island". / Hao, Xiuli; Luethje, Freja L.; Qin, Yanan; McDevitt, Sylvia Franke; Lutay, Nataliya; Hobman, Jon L.; Asiani, Karishma; Soncini, Fernando C.; German, Nadezhda; Zhang, Siyu; Zhu, Yong-Guan; Rensing, Christopher.

I: Applied Microbiology and Biotechnology, Vol. 99, Nr. 14, 2015, s. 5817-5824.

Forskningsoutput: TidskriftsbidragÖversiktsartikel

Harvard

Hao, X, Luethje, FL, Qin, Y, McDevitt, SF, Lutay, N, Hobman, JL, Asiani, K, Soncini, FC, German, N, Zhang, S, Zhu, Y-G & Rensing, C 2015, 'Survival in amoeba-a major selection pressure on the presence of bacterial copper and zinc resistance determinants? Identification of a "copper pathogenicity island"', Applied Microbiology and Biotechnology, vol. 99, nr. 14, s. 5817-5824. https://doi.org/10.1007/s00253-015-6749-0

APA

Hao, X., Luethje, F. L., Qin, Y., McDevitt, S. F., Lutay, N., Hobman, J. L., Asiani, K., Soncini, F. C., German, N., Zhang, S., Zhu, Y-G., & Rensing, C. (2015). Survival in amoeba-a major selection pressure on the presence of bacterial copper and zinc resistance determinants? Identification of a "copper pathogenicity island". Applied Microbiology and Biotechnology, 99(14), 5817-5824. https://doi.org/10.1007/s00253-015-6749-0

CBE

MLA

Vancouver

Author

Hao, Xiuli ; Luethje, Freja L. ; Qin, Yanan ; McDevitt, Sylvia Franke ; Lutay, Nataliya ; Hobman, Jon L. ; Asiani, Karishma ; Soncini, Fernando C. ; German, Nadezhda ; Zhang, Siyu ; Zhu, Yong-Guan ; Rensing, Christopher. / Survival in amoeba-a major selection pressure on the presence of bacterial copper and zinc resistance determinants? Identification of a "copper pathogenicity island". I: Applied Microbiology and Biotechnology. 2015 ; Vol. 99, Nr. 14. s. 5817-5824.

RIS

TY - JOUR

T1 - Survival in amoeba-a major selection pressure on the presence of bacterial copper and zinc resistance determinants? Identification of a "copper pathogenicity island"

AU - Hao, Xiuli

AU - Luethje, Freja L.

AU - Qin, Yanan

AU - McDevitt, Sylvia Franke

AU - Lutay, Nataliya

AU - Hobman, Jon L.

AU - Asiani, Karishma

AU - Soncini, Fernando C.

AU - German, Nadezhda

AU - Zhang, Siyu

AU - Zhu, Yong-Guan

AU - Rensing, Christopher

PY - 2015

Y1 - 2015

N2 - The presence of metal resistance determinants in bacteria usually is attributed to geological or anthropogenic metal contamination in different environments or associated with the use of antimicrobial metals in human healthcare or in agriculture. While this is certainly true, we hypothesize that protozoan predation and macrophage killing are also responsible for selection of copper/zinc resistance genes in bacteria. In this review, we outline evidence supporting this hypothesis, as well as highlight the correlation between metal resistance and pathogenicity in bacteria. In addition, we introduce and characterize the "copper pathogenicity island" identified in Escherichia coli and Salmonella strains isolated from copper- and zinc-fed Danish pigs.

AB - The presence of metal resistance determinants in bacteria usually is attributed to geological or anthropogenic metal contamination in different environments or associated with the use of antimicrobial metals in human healthcare or in agriculture. While this is certainly true, we hypothesize that protozoan predation and macrophage killing are also responsible for selection of copper/zinc resistance genes in bacteria. In this review, we outline evidence supporting this hypothesis, as well as highlight the correlation between metal resistance and pathogenicity in bacteria. In addition, we introduce and characterize the "copper pathogenicity island" identified in Escherichia coli and Salmonella strains isolated from copper- and zinc-fed Danish pigs.

KW - Copper

KW - Pathogenicity

KW - Amoeba

KW - Grazing resistance

U2 - 10.1007/s00253-015-6749-0

DO - 10.1007/s00253-015-6749-0

M3 - Review article

C2 - 26088177

VL - 99

SP - 5817

EP - 5824

JO - Applied Microbiology and Biotechnology

JF - Applied Microbiology and Biotechnology

SN - 1432-0614

IS - 14

ER -