Synthesis of aromatic C-xylosides by position inversion of glucose

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Abstract

Two formally C-xylosylated analogs to 2-naphthyl beta-D-xylopyranoside, which is known to initiate priming of glucosaminoglycan chains, were synthesized by a position inversion of glucose (i.e., position I becomes position 5). The D-C-xyloside showed priming, while the L-C-xyloside did not initiate priming. (c) 2006 Elsevier Ltd. All rights reserved.

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Nyckelord

Originalspråkengelska
Sidor (från-till)6659-6665
TidskriftBioorganic & Medicinal Chemistry
Volym14
Utgivningsnummer19
StatusPublished - 2006
PublikationskategoriForskning
Peer review utfördJa