Synthesis of C-1 indol-3-yl substituted tetrahydroisoquinoline derivatives via a Pictet-Spengler approach

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

A protocol for the diastereoselective synthesis of C-1 indol-3-yl substituted tetrahydroisoquinoline derivatives via Pictet-Spengler condensation with L-DOPA or L-DOPA derivatives and 1H-indole-3-carbaldehydes is presented. The protocol is used for the successful synthesis of several tetrahydroisoquinolines as well as diketopiperazine fused analogues. (C) 2012 Elsevier Ltd. All rights reserved.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Kemi

Nyckelord

Originalspråkengelska
Sidor (från-till)4966-4970
TidskriftTetrahedron Letters
Volym53
Utgivningsnummer37
StatusPublished - 2012
PublikationskategoriForskning
Peer review utfördJa