Synthesis of podoscyphic acid

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Podoscyphic acid 1, a fungal metabolite inhibiting RNA-directed DNA polymerises, was synthesised in four steps starting from dodecanal. The concluding ester hydrolysis of 4 was not feasible with chemical reagents, only enzymatic hydrolysis was mild enough to release the highly reactive natural product in good yields. (C) 2002 Elsevier Science Ltd. All rights reserved.

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Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Organisk kemi

Nyckelord

Originalspråkengelska
Sidor (från-till)891-893
TidskriftTetrahedron Letters
Volym43
Utgivningsnummer5
StatusPublished - 2002
PublikationskategoriForskning
Peer review utfördJa