The coagulation system and its function in early immune defense.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Blood coagulation has a Janus-faced role in infectious diseases. When systemically activated, it can cause serious complications associated with high morbidity and mortality. However, coagulation is also part of the innate immune system and its local activation has been found to play an important role in the early host response to infection. Though the latter aspect has been less investigated, phylogenetic studies have shown that many factors involved in coagulation have ancestral origins which are often combined with anti-microbial features. This review gives a general overview about the most recent advances in this area of research also referred to as immunothrombosis.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Kardiologi
Originalspråkengelska
Sidor (från-till)640-648
TidskriftThrombosis and Haemostasis
Volym112
Utgivningsnummer4
StatusPublished - 2014
PublikationskategoriForskning
Peer review utfördJa

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Related projects

Heiko Herwald

2010/01/01 → …

Projekt: Forskning

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