The effect of dextran 40 and Dazmegrel on early platelet deposition onto vascular grafts

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Platelet deposition onto double velour Dacron (n = 14) and double velour Dacron with internal collagen (n = 14) interposition grafts were examined experimentally. The accumulation was assessed by reinfusion of 111In labelled platelets and imaging with a scintillation camera. One group received Dextran-40 intravenously (n = 14) and one group received Dazmegrel (n = 14) intravenously. No graft occlusions were noted. Differences in effects of Dextran-40 and Dazmegrel were not observed. The study indicates a beneficial effect of infused Dextran-40 as well as Dazmegrel. The explanation might be reduced interaction graft wall versus blood-platelets.

Detaljer

Författare
  • Håkan Pärsson
  • Lars Norgren
  • Krassi Ivancev
  • Johan Thörne
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Kardiologi
Originalspråkengelska
Sidor (från-till)242-246
TidskriftVasa: European Journal of Vascular Medicine
Volym19
Utgåva nummer3
StatusPublished - 1990
PublikationskategoriForskning
Peer review utfördJa