The Kärger vs bi-exponential model: Theoretical insights and experimental validations
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The Kärger vs bi-exponential model : Theoretical insights and experimental validations. / Moutal, Nicolas; Nilsson, Markus; Topgaard, Daniel; Grebenkov, Denis.
I: Journal of Magnetic Resonance, Vol. 296, 2018, s. 72-78.Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift
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TY - JOUR
T1 - The Kärger vs bi-exponential model
T2 - Theoretical insights and experimental validations
AU - Moutal, Nicolas
AU - Nilsson, Markus
AU - Topgaard, Daniel
AU - Grebenkov, Denis
PY - 2018
Y1 - 2018
N2 - We revise three common models accounting for water exchange in pulsed-gradient spin-echo measurements: a bi-exponential model with time-dependent water fractions, the Kärger model, and a modified Kärger model designed for restricted diffusion, e.g. inside cells. The three models are compared and applied to experimental data from yeast cell suspensions. The Kärger model and the modified Kärger model yield very close results and accurately fit the data. The bi-exponential model, although less rigorous, has a natural physical interpretation and suggests a new experimental modality to estimate the water exchange time.
AB - We revise three common models accounting for water exchange in pulsed-gradient spin-echo measurements: a bi-exponential model with time-dependent water fractions, the Kärger model, and a modified Kärger model designed for restricted diffusion, e.g. inside cells. The three models are compared and applied to experimental data from yeast cell suspensions. The Kärger model and the modified Kärger model yield very close results and accurately fit the data. The bi-exponential model, although less rigorous, has a natural physical interpretation and suggests a new experimental modality to estimate the water exchange time.
KW - Bi-exponential model
KW - Kärger model
KW - Permeability
KW - PGSE
KW - Water exchange
KW - Yeast cells
U2 - 10.1016/j.jmr.2018.08.015
DO - 10.1016/j.jmr.2018.08.015
M3 - Article
C2 - 30223153
AN - SCOPUS:85053311723
VL - 296
SP - 72
EP - 78
JO - Journal of Magnetic Resonance
JF - Journal of Magnetic Resonance
SN - 1096-0856
ER -