The Kärger vs bi-exponential model: Theoretical insights and experimental validations

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Standard

The Kärger vs bi-exponential model : Theoretical insights and experimental validations. / Moutal, Nicolas; Nilsson, Markus; Topgaard, Daniel; Grebenkov, Denis.

I: Journal of Magnetic Resonance, Vol. 296, 2018, s. 72-78.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Harvard

APA

CBE

MLA

Vancouver

Author

RIS

TY - JOUR

T1 - The Kärger vs bi-exponential model

T2 - Theoretical insights and experimental validations

AU - Moutal, Nicolas

AU - Nilsson, Markus

AU - Topgaard, Daniel

AU - Grebenkov, Denis

PY - 2018

Y1 - 2018

N2 - We revise three common models accounting for water exchange in pulsed-gradient spin-echo measurements: a bi-exponential model with time-dependent water fractions, the Kärger model, and a modified Kärger model designed for restricted diffusion, e.g. inside cells. The three models are compared and applied to experimental data from yeast cell suspensions. The Kärger model and the modified Kärger model yield very close results and accurately fit the data. The bi-exponential model, although less rigorous, has a natural physical interpretation and suggests a new experimental modality to estimate the water exchange time.

AB - We revise three common models accounting for water exchange in pulsed-gradient spin-echo measurements: a bi-exponential model with time-dependent water fractions, the Kärger model, and a modified Kärger model designed for restricted diffusion, e.g. inside cells. The three models are compared and applied to experimental data from yeast cell suspensions. The Kärger model and the modified Kärger model yield very close results and accurately fit the data. The bi-exponential model, although less rigorous, has a natural physical interpretation and suggests a new experimental modality to estimate the water exchange time.

KW - Bi-exponential model

KW - Kärger model

KW - Permeability

KW - PGSE

KW - Water exchange

KW - Yeast cells

U2 - 10.1016/j.jmr.2018.08.015

DO - 10.1016/j.jmr.2018.08.015

M3 - Article

C2 - 30223153

AN - SCOPUS:85053311723

VL - 296

SP - 72

EP - 78

JO - Journal of Magnetic Resonance

JF - Journal of Magnetic Resonance

SN - 1096-0856

ER -