The new cell irradiation facility at the Lund nuclear probe

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

The CELLION project is directed towards the studies on cellular response to targeted single ions. This paper gives an account of the modifications made at the Lund sub-micron beam line in order to create a Single Ion Hit Facility for biological applications within the CELLION project. The most relevant new feature is the specially developed software used to locate the cells. A program for cell recognition and localization that gives the coordinates of the centre of the cells has been designed. The recognition is made online. A picture taken by a microscope is used as input parameter for the recognition program. Using V79 Chinese hamster cells, the recognition procedure can be done in less than 0.5 s for a picture size of 800 x 600 pixels with approximately 96% efficiency. This paper also reports target accuracy test results and the first non-targeted irradiation procedure performed at the Lund sub-micron beam line. (c) 2007 Elsevier B.V. All rights reserved.

Detaljer

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Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Infektionsmedicin

Nyckelord

Originalspråkengelska
Sidor (från-till)91-96
TidskriftNuclear Instruments & Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms
Volym260
Utgåva nummer1
StatusPublished - 2007
PublikationskategoriForskning
Peer review utfördJa
Evenemang10th International Conference on Nuclear Microprobe Technology and Applications and 2nd International Workshop on Proton Beam Writing - Singapore, Singapore
Varaktighet: 2006 jul 92006 jul 14

Relaterad forskningsoutput

Natalia Arteaga, 2010, Department of Physics, Lund University. 133 s.

Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

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