The proportion cured of patients with resected stage ii–iii cutaneous melanoma in sweden

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Abstract

Background: Cure proportion represents the proportion of patients who experience the same mortality rate as the general population and can be estimated together with the survival of the proportion experiencing excess mortality (the uncured). The aim was to estimate the cure proportions and survival among uncured stage II–III cutaneous melanoma (CM) patients. Methods: 1‐ and 5‐year relative survival ratios, cure proportions and the median survival times of uncured stage II–III CM patients in Sweden (n = 6466) were calculated based on data from the nationwide popu-lation‐based Swedish Melanoma Register 2005–2013 with a follow‐up through 2018. Results: Stages IIB and IIC showed significant differences in standardized cure proportions vs. stage IIA CM (0.80 (95% CI 0.77–0.83) stage IIA; 0.62 (95% CI 0.59–0.66) stage IIB; 0.42 (95% CI 0.37–0.46) for stage IIC). Significant differences in standardized cure proportions were found for stages IIIB and IIIC‐D CM vs. stage IIIA (0.76 (95% CI 0.68–0.84) stage IIIA; 0.52 (95% CI 0.45–0.59) stage IIIB; 0.35 (95% CI 0.30– 0.39) for stage IIIC–D). Conclusions: The results are emphasizing the poor prognosis with low proportions cured by surgery only for sub‐groups of stage II–III CM, specifically within stages IIB–C CM.

Detaljer

Författare
  • Hanna Eriksson
  • Deborah Utjés
  • Roger Bagge Olofsson
  • Peter Gillgren
  • Karolin Isaksson
  • Jan Lapins
  • Inkeri Leonardsson Schultz
  • Johan Lyth
  • Therese M.L. Andersson
Enheter & grupper
Externa organisationer
  • Karolinska University Hospital
  • Sahlgrenska Academy
  • Sahlgrenska University Hospital
  • Karolinska Institute
  • Uppsala University Hospital
  • Central Hospital Kristianstad
  • Linköping University
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Cancer och onkologi

Nyckelord

Originalspråkengelska
Artikelnummer2456
TidskriftCancers
Volym13
Utgåva nummer10
StatusPublished - 2021 maj 2
PublikationskategoriForskning
Peer review utfördJa