Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting

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Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting. / Schmitt, Jochen; Spuls, Phyllis; Boers, Maarten; Thomas, Kim; Chalmers, Joanne; Roekevisch, Evelien; Schram, Mandy; Allsopp, Richard; Aoki, Valeria; Apfelbacher, Christian; Bruijnzeel-Koomen, Carla; Bruin-Weller, Marjolein; Charman, Carolyn; Cohen, Arnon; Dohil, Magdalene; Flohr, Carsten; Furue, Masutaka; Gieler, Uwe; Hooft, Lotty; Humphreys, Rosemary; Ishii, Henrique Akira; Katayama, Ichiro; Kouwenhoven, Willem; Langan, Sinead; Lewis-Jones, Sue; Merhand, Stephanie; Murota, Hiroyuki; Murrell, Dedee F.; Nankervis, Helen; Ohya, Yukihiro; Oranje, Arnold; Otsuka, Hiromi; Paul, Carle; Rosenbluth, Yael; Saeki, Hidehisa; Schuttelaar, Marie-Louise; Stalder, Jean-Francois; Svensson, Åke; Takaoka, Roberto; Wahlgren, Carl-Fredrik; Weidinger, Stephan; Wollenberg, Andreas; Williams, Hywel.

I: Allergy, Vol. 67, Nr. 9, 2012, s. 1111-1117.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Harvard

Schmitt, J, Spuls, P, Boers, M, Thomas, K, Chalmers, J, Roekevisch, E, Schram, M, Allsopp, R, Aoki, V, Apfelbacher, C, Bruijnzeel-Koomen, C, Bruin-Weller, M, Charman, C, Cohen, A, Dohil, M, Flohr, C, Furue, M, Gieler, U, Hooft, L, Humphreys, R, Ishii, HA, Katayama, I, Kouwenhoven, W, Langan, S, Lewis-Jones, S, Merhand, S, Murota, H, Murrell, DF, Nankervis, H, Ohya, Y, Oranje, A, Otsuka, H, Paul, C, Rosenbluth, Y, Saeki, H, Schuttelaar, M-L, Stalder, J-F, Svensson, Å, Takaoka, R, Wahlgren, C-F, Weidinger, S, Wollenberg, A & Williams, H 2012, 'Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting', Allergy, vol. 67, nr. 9, s. 1111-1117. https://doi.org/10.1111/j.1398-9995.2012.02874.x

APA

Schmitt, J., Spuls, P., Boers, M., Thomas, K., Chalmers, J., Roekevisch, E., ... Williams, H. (2012). Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting. Allergy, 67(9), 1111-1117. https://doi.org/10.1111/j.1398-9995.2012.02874.x

CBE

Schmitt J, Spuls P, Boers M, Thomas K, Chalmers J, Roekevisch E, Schram M, Allsopp R, Aoki V, Apfelbacher C, Bruijnzeel-Koomen C, Bruin-Weller M, Charman C, Cohen A, Dohil M, Flohr C, Furue M, Gieler U, Hooft L, Humphreys R, Ishii HA, Katayama I, Kouwenhoven W, Langan S, Lewis-Jones S, Merhand S, Murota H, Murrell DF, Nankervis H, Ohya Y, Oranje A, Otsuka H, Paul C, Rosenbluth Y, Saeki H, Schuttelaar M-L, Stalder J-F, Svensson Å, Takaoka R, Wahlgren C-F, Weidinger S, Wollenberg A, Williams H. 2012. Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting. Allergy. 67(9):1111-1117. https://doi.org/10.1111/j.1398-9995.2012.02874.x

MLA

Vancouver

Author

Schmitt, Jochen ; Spuls, Phyllis ; Boers, Maarten ; Thomas, Kim ; Chalmers, Joanne ; Roekevisch, Evelien ; Schram, Mandy ; Allsopp, Richard ; Aoki, Valeria ; Apfelbacher, Christian ; Bruijnzeel-Koomen, Carla ; Bruin-Weller, Marjolein ; Charman, Carolyn ; Cohen, Arnon ; Dohil, Magdalene ; Flohr, Carsten ; Furue, Masutaka ; Gieler, Uwe ; Hooft, Lotty ; Humphreys, Rosemary ; Ishii, Henrique Akira ; Katayama, Ichiro ; Kouwenhoven, Willem ; Langan, Sinead ; Lewis-Jones, Sue ; Merhand, Stephanie ; Murota, Hiroyuki ; Murrell, Dedee F. ; Nankervis, Helen ; Ohya, Yukihiro ; Oranje, Arnold ; Otsuka, Hiromi ; Paul, Carle ; Rosenbluth, Yael ; Saeki, Hidehisa ; Schuttelaar, Marie-Louise ; Stalder, Jean-Francois ; Svensson, Åke ; Takaoka, Roberto ; Wahlgren, Carl-Fredrik ; Weidinger, Stephan ; Wollenberg, Andreas ; Williams, Hywel. / Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting. I: Allergy. 2012 ; Vol. 67, Nr. 9. s. 1111-1117.

RIS

TY - JOUR

T1 - Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting

AU - Schmitt, Jochen

AU - Spuls, Phyllis

AU - Boers, Maarten

AU - Thomas, Kim

AU - Chalmers, Joanne

AU - Roekevisch, Evelien

AU - Schram, Mandy

AU - Allsopp, Richard

AU - Aoki, Valeria

AU - Apfelbacher, Christian

AU - Bruijnzeel-Koomen, Carla

AU - Bruin-Weller, Marjolein

AU - Charman, Carolyn

AU - Cohen, Arnon

AU - Dohil, Magdalene

AU - Flohr, Carsten

AU - Furue, Masutaka

AU - Gieler, Uwe

AU - Hooft, Lotty

AU - Humphreys, Rosemary

AU - Ishii, Henrique Akira

AU - Katayama, Ichiro

AU - Kouwenhoven, Willem

AU - Langan, Sinead

AU - Lewis-Jones, Sue

AU - Merhand, Stephanie

AU - Murota, Hiroyuki

AU - Murrell, Dedee F.

AU - Nankervis, Helen

AU - Ohya, Yukihiro

AU - Oranje, Arnold

AU - Otsuka, Hiromi

AU - Paul, Carle

AU - Rosenbluth, Yael

AU - Saeki, Hidehisa

AU - Schuttelaar, Marie-Louise

AU - Stalder, Jean-Francois

AU - Svensson, Åke

AU - Takaoka, Roberto

AU - Wahlgren, Carl-Fredrik

AU - Weidinger, Stephan

AU - Wollenberg, Andreas

AU - Williams, Hywel

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venerology (013241320)

PY - 2012

Y1 - 2012

N2 - The use of nonstandardized and inadequately validated outcome measures in atopic eczema trials is a major obstacle to practising evidence-based dermatology. The Harmonising Outcome Measures for Eczema (HOME) initiative is an international multiprofessional group dedicated to atopic eczema outcomes research. In June 2011, the HOME initiative conducted a consensus study involving 43 individuals from 10 countries, representing different stakeholders (patients, clinicians, methodologists, pharmaceutical industry) to determine core outcome domains for atopic eczema trials, to define quality criteria for atopic eczema outcome measures and to prioritize topics for atopic eczema outcomes research. Delegates were given evidence-based information, followed by structured group discussion and anonymous consensus voting. Consensus was achieved to include clinical signs, symptoms, long-term control of flares and quality of life into the core set of outcome domains for atopic eczema trials. The HOME initiative strongly recommends including and reporting these core outcome domains as primary or secondary endpoints in all future atopic eczema trials. Measures of these core outcome domains need to be valid, sensitive to change and feasible. Prioritized topics of the HOME initiative are the identification/development of the most appropriate instruments for the four core outcome domains. HOME is open to anyone with an interest in atopic eczema outcomes research.

AB - The use of nonstandardized and inadequately validated outcome measures in atopic eczema trials is a major obstacle to practising evidence-based dermatology. The Harmonising Outcome Measures for Eczema (HOME) initiative is an international multiprofessional group dedicated to atopic eczema outcomes research. In June 2011, the HOME initiative conducted a consensus study involving 43 individuals from 10 countries, representing different stakeholders (patients, clinicians, methodologists, pharmaceutical industry) to determine core outcome domains for atopic eczema trials, to define quality criteria for atopic eczema outcome measures and to prioritize topics for atopic eczema outcomes research. Delegates were given evidence-based information, followed by structured group discussion and anonymous consensus voting. Consensus was achieved to include clinical signs, symptoms, long-term control of flares and quality of life into the core set of outcome domains for atopic eczema trials. The HOME initiative strongly recommends including and reporting these core outcome domains as primary or secondary endpoints in all future atopic eczema trials. Measures of these core outcome domains need to be valid, sensitive to change and feasible. Prioritized topics of the HOME initiative are the identification/development of the most appropriate instruments for the four core outcome domains. HOME is open to anyone with an interest in atopic eczema outcomes research.

KW - atopic dermatitis

KW - consensus study

KW - measurement

KW - outcome domain

KW - study

KW - endpoint

U2 - 10.1111/j.1398-9995.2012.02874.x

DO - 10.1111/j.1398-9995.2012.02874.x

M3 - Article

VL - 67

SP - 1111

EP - 1117

JO - Allergy

T2 - Allergy

JF - Allergy

SN - 1398-9995

IS - 9

ER -