Troponin T levels associated with genetic variants in NOTCH2 and MTNR1B in women with psychosis

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Psychosis patients have increased prevalence of metabolic disorders, which increase the risk for cardiovascular disease. Elevated troponin T level is an early biomarker of cardiovascular damage. We tested for association between troponin T levels and genetic risk variants of elevated blood glucose level in psychosis. Glucose and troponin T levels correlated positively. MTNR1B rs10830963 and NOTCH2 rs10923931 associated with troponin T levels in women, adjusted for glucose levels. These findings may indicate metabolic genetic influences on troponin T levels among women with psychosis.

Detaljer

Författare
  • Dzana Sudic Hukic
  • Catharina Lavebratt
  • Eric Olsson
  • Claes-Göran Östenson
  • Sven V. Eriksson
  • David Erlinge
  • Martin Schalling
  • Urban Ösby
Enheter & grupper
Externa organisationer
  • Karolinska Institute
  • Karolinska University Hospital
  • Danderyd Hospital
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Psykiatri

Nyckelord

Originalspråkengelska
Sidor (från-till)217-220
Antal sidor4
TidskriftPsychiatry Research
Volym250
StatusPublished - 2017 apr 1
PublikationskategoriForskning
Peer review utfördJa