γ-Tubulin⁻γ-Tubulin Interactions as the Basis for the Formation of a Meshwork

Forskningsoutput: TidskriftsbidragÖversiktsartikel

Abstract

In cytoplasm, protein γ-tubulin joins with various γ-tubulin complex proteins (GCPs) to form a heterotetramer γ-tubulin small complex (γ-TuSC) that can grow into a ring-shaped structure called the γ-tubulin ring complex (γ-TuRC). Both γ-TuSC and γ-TuRC are required for microtubule nucleation. Recent knowledge on γ-tubulin with regard to its cellular functions beyond participation in its creation of microtubules suggests that this protein forms a cellular meshwork. The present review summarizes the recognized functions of γ-tubulin and aims to unite the current views on this protein.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Skåne University Hospital
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Cell- och molekylärbiologi
Originalspråkengelska
Artikelnummer3245
TidskriftInternational Journal of Molecular Sciences
Volym19
Utgivningsnummer10
StatusPublished - 2018 okt 19
PublikationskategoriForskning
Peer review utfördJa