Uptake of thymidine in lymphoma cells obtained through fine-needle aspiration biopsy. Relation to prognosis in non-hodgkin's lymphomas

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

In vitro uptake of tritiated thymidine was studied in autoradiographic preparations of lymphoma cell suspensions obtained through fine-needle aspiration biopsy from 28 patients with non-Hodgkin's lymphoma. The labelling indices (LI ) were highest in patients with histiocytic or poorly differentiated lymphocytic lymphoma. During a two-year period there was a significant correlation between LI and survival, i.e., high LI were associated with a poor prognosis. The results indicate that, in addition to morphology, estimation of the proliferative activity of lymphoma cells may be of clinical significance. © 1981, Pergamon Press Ltd.. All rights reserved.

Detaljer

Författare
Enheter & grupper
Externa organisationer
  • Skåne University Hospital
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Cancer och onkologi
Originalspråkengelska
Sidor (från-till)1229-1233
Antal sidor5
TidskriftEuropean Journal of Cancer and Clinical Oncology
Volym17
Utgåva nummer11
StatusPublished - 1981
PublikationskategoriForskning
Peer review utfördJa