Validation of a brief Multicultural Cognitive Examination (MCE) for evaluation of dementia

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Validation of a brief Multicultural Cognitive Examination (MCE) for evaluation of dementia. / Nielsen, T. Rune; Segers, Kurt; Vanderaspoilden, Valérie; Beinhoff, Ulrike; Minthon, Lennart; Pissiota, Anna; Bekkhus-Wetterberg, Peter; Bjørkløf, Guro Hanevold; Tsolaki, Magda; Gkioka, Mara; Waldemar, Gunhild.

I: International Journal of Geriatric Psychiatry, 22.03.2019.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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Nielsen, TR, Segers, K, Vanderaspoilden, V, Beinhoff, U, Minthon, L, Pissiota, A, Bekkhus-Wetterberg, P, Bjørkløf, GH, Tsolaki, M, Gkioka, M & Waldemar, G 2019, 'Validation of a brief Multicultural Cognitive Examination (MCE) for evaluation of dementia', International Journal of Geriatric Psychiatry. https://doi.org/10.1002/gps.5099

APA

CBE

Nielsen TR, Segers K, Vanderaspoilden V, Beinhoff U, Minthon L, Pissiota A, Bekkhus-Wetterberg P, Bjørkløf GH, Tsolaki M, Gkioka M, Waldemar G. 2019. Validation of a brief Multicultural Cognitive Examination (MCE) for evaluation of dementia. International Journal of Geriatric Psychiatry. https://doi.org/10.1002/gps.5099

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Nielsen, T. Rune ; Segers, Kurt ; Vanderaspoilden, Valérie ; Beinhoff, Ulrike ; Minthon, Lennart ; Pissiota, Anna ; Bekkhus-Wetterberg, Peter ; Bjørkløf, Guro Hanevold ; Tsolaki, Magda ; Gkioka, Mara ; Waldemar, Gunhild. / Validation of a brief Multicultural Cognitive Examination (MCE) for evaluation of dementia. I: International Journal of Geriatric Psychiatry. 2019.

RIS

TY - JOUR

T1 - Validation of a brief Multicultural Cognitive Examination (MCE) for evaluation of dementia

AU - Nielsen, T. Rune

AU - Segers, Kurt

AU - Vanderaspoilden, Valérie

AU - Beinhoff, Ulrike

AU - Minthon, Lennart

AU - Pissiota, Anna

AU - Bekkhus-Wetterberg, Peter

AU - Bjørkløf, Guro Hanevold

AU - Tsolaki, Magda

AU - Gkioka, Mara

AU - Waldemar, Gunhild

PY - 2019/3/22

Y1 - 2019/3/22

N2 - Background: The aims of this study were to present the psychometric properties of a newly designed cognitive screening instrument, the Multicultural Cognitive Examination (MCE), and to compare it with the Rowland Universal Dementia Assessment Scale (RUDAS) in a multicultural population. Methods: The study was a Western European cross-sectional multicenter study. The MCE consists of four components evaluating separate cognitive functions and was constructed by adding measures of memory, verbal fluency, and visuospatial function to the RUDAS to create a scale with 0 to 100 points. Results: A total of 66 patients with dementia and 123 cognitively intact participants were included across six memory clinics; 96 had minority ethnic background, and 93 had majority ethnic background. Moderate to large differences were present between patients with dementia and control participants on all MCE components. The MCE significantly improved diagnostic accuracy compared with using the RUDAS alone, with area under the curves of.918,.984, and.991 for the RUDAS, MCE composite, and demographically corrected composite scores, respectively. Diagnostic accuracy of the MCE did not significantly differ between minority and majority ethnic groups. Across MCE subcomponents, patients with Alzheimer's disease (AD) dementia performed significantly poorer on the memory component compared with those with non-AD dementia. Conclusions: The MCE is a brief cross-cultural cognitive screening instrument that expands evaluation of the cognitive functions covered by the RUDAS, does not require any specialized training, and may be useful for classification of mild dementia or dementia subtypes.

AB - Background: The aims of this study were to present the psychometric properties of a newly designed cognitive screening instrument, the Multicultural Cognitive Examination (MCE), and to compare it with the Rowland Universal Dementia Assessment Scale (RUDAS) in a multicultural population. Methods: The study was a Western European cross-sectional multicenter study. The MCE consists of four components evaluating separate cognitive functions and was constructed by adding measures of memory, verbal fluency, and visuospatial function to the RUDAS to create a scale with 0 to 100 points. Results: A total of 66 patients with dementia and 123 cognitively intact participants were included across six memory clinics; 96 had minority ethnic background, and 93 had majority ethnic background. Moderate to large differences were present between patients with dementia and control participants on all MCE components. The MCE significantly improved diagnostic accuracy compared with using the RUDAS alone, with area under the curves of.918,.984, and.991 for the RUDAS, MCE composite, and demographically corrected composite scores, respectively. Diagnostic accuracy of the MCE did not significantly differ between minority and majority ethnic groups. Across MCE subcomponents, patients with Alzheimer's disease (AD) dementia performed significantly poorer on the memory component compared with those with non-AD dementia. Conclusions: The MCE is a brief cross-cultural cognitive screening instrument that expands evaluation of the cognitive functions covered by the RUDAS, does not require any specialized training, and may be useful for classification of mild dementia or dementia subtypes.

KW - Alzheimer's disease

KW - Cognitive assessment

KW - dementia

KW - diagnostic accuracy

KW - ethnic groups

KW - multicultural

KW - RUDAS

U2 - 10.1002/gps.5099

DO - 10.1002/gps.5099

M3 - Article

JO - International Journal of Geriatric Psychiatry

T2 - International Journal of Geriatric Psychiatry

JF - International Journal of Geriatric Psychiatry

SN - 1099-1166

ER -