Ventricular kinetic energy in young fontan patients

Forskningsoutput: TidskriftsbidragPublicerat konferensabstract

Abstract

Introduction: Four-dimensional (4D) flow magnetic resonance imaging (MRI) enables kinetic energy (KE) quantification of intraventricular blood flow. In this study we aimed to quantify the KE in in patients with univentricular heart and to assess the change in the KE after different types of interventions. Methods: 4D flow MRI was acquired in patients with Fontan circulation (n=12; median age 12, range 3-29 years) and in healthy volunteers (n =8; median age 26, range 23-36 years). MRI was repeated after transcatheter embolization of significant aortopulmonary collaterals (APC; n = 1), after stenting of left pulmonary artery (n=1) and after surgical replacement of hepatic flow tunnel with a Y graft due to significant central pulmonary artery stenosis with secondary formation of arteriovenous (AV) fistulas in the right lung (n= 1). Intraventricular KE was calculated throughout the cardiac cycle and indexed to stroke volume (SV). Results: The systole/diastole ratio of KE in Fontan patients was similar to the ratio of the controls' left ventricle (LV) or right ventricle (RV) depending on the ventricular morphology (Coheńs kappa =1.0). Peak systolic KE/SV did not differ in patients compared to the LV in controls (0.016 ± 0.006 mJ/ml vs 0.020 ±0.004 mJ/ml, p= 0.09). Peak diastolic KE/SV in Fontan patients was lower than in the LV of the control group (0.028 ±0.010 vs 0.057± 0.011 mJ/ml, p

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Pediatrik

Nyckelord

Originalspråkengelska
Sidor (från-till)S64
Antal sidor1
TidskriftCardiology in the Young
Volym26
UtgivningsnummerSuppl 1
StatusPublished - 2016 maj 1
PublikationskategoriForskning
Peer review utfördJa
Evenemang50th Annual Meeting of the Association for European Paediatric and Congenital Cardiology - , Italien
Varaktighet: 2016 jun 12016 jun 4