Vitamin K2 (Menaquinone-7) Supplementation and its Effect on Glucose Tolerance Test in Healthy Volunteers

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Vitamin K2 (Menaquinone-7) Supplementation and its Effect on Glucose Tolerance Test in Healthy Volunteers. / Dahlberg, Sofia; Larsson, Daniel; Romner, André ; Schott, ulf.

I: Journal of Diabetes Management and Metabolism, Vol. 2, Nr. JDMM-10002, JDMM-10002, 11.03.2019, s. 1-5.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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TY - JOUR

T1 - Vitamin K2 (Menaquinone-7) Supplementation and its Effect on Glucose Tolerance Test in Healthy Volunteers

AU - Dahlberg, Sofia

AU - Larsson, Daniel

AU - Romner, André

AU - Schott, ulf

N1 - Open access. Publicerat T5-ISEX uppsats.

PY - 2019/3/11

Y1 - 2019/3/11

N2 - Background: Type 2 diabetes can often be managed by healthier diet and exercise in early stages of the disease, but as it progresses oral medication is needed and later on the patients will require insulin to survive. Vitamin K is a fat soluble vitamin that is a cofactor in gamma-carboxylation and activation of coagulation proteins produced in the liver. There are also extrahepatic proteins named Gla proteins that require vitamin K to be activated. Previous studies suggest that some of these proteins have a connection to calcification of vessels, bone mineralization, metabolic syndrome and diabetes, but results are conflicting.

AB - Background: Type 2 diabetes can often be managed by healthier diet and exercise in early stages of the disease, but as it progresses oral medication is needed and later on the patients will require insulin to survive. Vitamin K is a fat soluble vitamin that is a cofactor in gamma-carboxylation and activation of coagulation proteins produced in the liver. There are also extrahepatic proteins named Gla proteins that require vitamin K to be activated. Previous studies suggest that some of these proteins have a connection to calcification of vessels, bone mineralization, metabolic syndrome and diabetes, but results are conflicting.

KW - Diabetes management

KW - Vitamin K/metabolism

KW - coagulation

KW - Thromboelastography

M3 - Article

VL - 2

SP - 1

EP - 5

JO - Journal of Diabetes Management and Metabolism

T2 - Journal of Diabetes Management and Metabolism

JF - Journal of Diabetes Management and Metabolism

IS - JDMM-10002

M1 - JDMM-10002

ER -