Why do chest compressions aid delayed defibrillation?

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Why do chest compressions aid delayed defibrillation? / Chambertain, Douglas; Frenneaux, Michael; Steen, Stig; Smith, Andrew.

I: Resuscitation, Vol. 77, Nr. 1, 2008, s. 10-15.

Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

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Chambertain, Douglas ; Frenneaux, Michael ; Steen, Stig ; Smith, Andrew. / Why do chest compressions aid delayed defibrillation?. I: Resuscitation. 2008 ; Vol. 77, Nr. 1. s. 10-15.

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TY - JOUR

T1 - Why do chest compressions aid delayed defibrillation?

AU - Chambertain, Douglas

AU - Frenneaux, Michael

AU - Steen, Stig

AU - Smith, Andrew

PY - 2008

Y1 - 2008

N2 - The new resuscitation guidelines permit compressions before delayed, defibrillation, a change that has generally been welcomed. The benefits are generally assumed to relate to the immediate provision of limited coronary perfusion with protection or replenishment of myocardial metabolic reserves. In this paper we argue that the concept is inadequate to explain many experimental and clinical. observations made during resuscitation attempts. We argue that changes in the size and shape of the ventricles are the most important reason for the narrow window of opportunity for defibrillation alone and for the value of compressions in extending this period. We also draw attention to the implication for clinical resuscitation and to one aspect of the current guidelines of the European Resuscitation Council that we believe to be inconsistent with the evidence that we review. (C) 2007 Elsevier Ireland Ltd. All rights reserved.

AB - The new resuscitation guidelines permit compressions before delayed, defibrillation, a change that has generally been welcomed. The benefits are generally assumed to relate to the immediate provision of limited coronary perfusion with protection or replenishment of myocardial metabolic reserves. In this paper we argue that the concept is inadequate to explain many experimental and clinical. observations made during resuscitation attempts. We argue that changes in the size and shape of the ventricles are the most important reason for the narrow window of opportunity for defibrillation alone and for the value of compressions in extending this period. We also draw attention to the implication for clinical resuscitation and to one aspect of the current guidelines of the European Resuscitation Council that we believe to be inconsistent with the evidence that we review. (C) 2007 Elsevier Ireland Ltd. All rights reserved.

KW - ventricular interaction

KW - pathophysiology

KW - cardiac arrest compressions

KW - defibrittation

KW - coronary perfusion pressure

KW - guidelines

U2 - 10.1016/j.resuscitation.2007.11.010

DO - 10.1016/j.resuscitation.2007.11.010

M3 - Debate/Note/Editorial

VL - 77

SP - 10

EP - 15

JO - Resuscitation

JF - Resuscitation

SN - 1873-1570

IS - 1

ER -