Why Do Sex Chromosomes Stop Recombining?

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

It is commonly assumed that sex chromosomes evolve recombination suppression because selection favours linkage between sex-determining and sexually antagonistic genes. However, although the role of sexual antagonism during sex chromosome evolution has attained strong support from theory, experimental and observational evidence is rare or equivocal. Here, we highlight alternative, often neglected, hypotheses for recombination suppression on sex chromosomes, which invoke meiotic drive, heterozygote advantage, and genetic drift, respectively. We contrast the hypotheses, the situations when they are likely to be of importance, and outline why it is surprisingly difficult to test them. Lastly, we discuss future research directions (including modelling, population genomics, comparative approaches, and experiments) to disentangle the different hypotheses of sex chromosome evolution.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Genetik

Nyckelord

Originalspråkengelska
Sidor (från-till)492-503
TidskriftTrends in Genetics
Volym34
Utgivningsnummer7
Tidigt onlinedatum2018 apr 30
StatusPublished - 2018 jul
PublikationskategoriForskning
Peer review utfördJa